YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: cel-1
Organism: Caenorhabditis elegans
Length: 573 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cel-1.

Description E-value Query
Range
Subject
Range
gi|45708973, gi|... - gi|47575756|ref|NP_001001222.1| RNA guanylyltransferase and 5'-phosphatase [Xenopus (Silurana) tropi...
346.0 [0..3] [573..6]

Back

Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLPDRWLHC PKTGTLINNL FFPFKTPLCK MYDNQIAERR YQFHPAEVFS HPHLHGKKIG  60
   61 LWIDLTNTDR YYFREEVTEH ECIYHKMKMA GRGVSPTQED TDNFIKLVQE FHKKYPDRVV 120
  121 GVHCTHGFNR TGFLIAAYLF QVEEYGLDAA IGEFAENRQK GIYKQDYIDD LFARYDPTED 180
  181 DKILAPEKPD WEREMS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 2c46A
Description: CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [197-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGMSTQIDNG RPSTSQQIPA TNGNNNQNGN QLSGGGDNSK LFMDGLIRGV KVCEDEGKKS  60
   61 MLQAKIKNLC KYNKQGFPGL QPVSLSRGNI NLLEQESYMV SWKADGMRYI IYINDGDVYA 120
  121 FDRDNEVFEI ENLDFVTKNG APLMETLVDT EVIIDKVEIN GAM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.38
Match: 1ckmA
Description: RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mRNA guanylyltransferase activity 8.44951560480445 bayes_pls_golite062009
RNA guanylyltransferase activity 8.02773775185769 bayes_pls_golite062009
guanylyltransferase activity 5.17049957294188 bayes_pls_golite062009
ligase activity 2.32117041900947 bayes_pls_golite062009
ligase activity, forming phosphoric ester bonds 2.12202868529213 bayes_pls_golite062009
DNA ligase activity 2.10005856611468 bayes_pls_golite062009
catalytic activity 1.98004058504857 bayes_pls_golite062009
binding 1.6492328714954 bayes_pls_golite062009
nucleic acid binding 1.36512645572174 bayes_pls_golite062009
DNA binding 1.30570045339175 bayes_pls_golite062009
DNA ligase (ATP) activity 0.353057247533014 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.293080071585386 bayes_pls_golite062009
protein binding 0.244939883018638 bayes_pls_golite062009
ATP binding 0.0764964990255529 bayes_pls_golite062009
adenyl ribonucleotide binding 0.0486642748854728 bayes_pls_golite062009
adenyl nucleotide binding 0.0414617030999805 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [360-573]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDQPRMLIYD IMRFNSVNVM KEPFYKRFEI IKTEIIDMRT AAFKTGRLKH ENQIMSVRRK  60
   61 DFYDLEATAK LFGPKFVQHV GHEIDGLIFQ PKKTKYETGR CDKVLKWKPP SHNSVDFLLK 120
  121 VEKKCKEGML PEWIGYLFVQ NLSDPFGTMK ATATLKKYHN KIIECTLLVD NQGRPKEWKF 180
  181 MRERTDKSLP NGLRTAENVV ETMVNPVTET YLIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1x9nA
Description: Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mRNA guanylyltransferase activity 8.90512192081791 bayes_pls_golite062009
RNA guanylyltransferase activity 8.46124967325993 bayes_pls_golite062009
guanylyltransferase activity 5.45528434251369 bayes_pls_golite062009
ligase activity, forming phosphoric ester bonds 2.90848936326491 bayes_pls_golite062009
DNA ligase activity 2.88630907730339 bayes_pls_golite062009
ligase activity 2.7348192562888 bayes_pls_golite062009
catalytic activity 2.15370807854636 bayes_pls_golite062009
binding 1.63149986094272 bayes_pls_golite062009
nucleic acid binding 1.39097817404242 bayes_pls_golite062009
DNA binding 1.33524321669723 bayes_pls_golite062009
DNA ligase (ATP) activity 1.02324195596817 bayes_pls_golite062009
DNA ligase (NAD+) activity 0.571203360462711 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.287720615514972 bayes_pls_golite062009
protein binding 0.229784545879049 bayes_pls_golite062009
ATP binding 0.17947590671995 bayes_pls_golite062009
adenyl ribonucleotide binding 0.148991737494582 bayes_pls_golite062009
adenyl nucleotide binding 0.138964074823321 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle