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View Structure Prediction Details

Protein: mmaa-1
Organism: Caenorhabditis elegans
Length: 298 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mmaa-1.

Description E-value Query
Range
Subject
Range
mmaa-1 - status:Confirmed UniProt:Q22111 protein_id:AAA82408.2
202.0 [0..1] [298..102]
gi|76638353, gi|... - gi|76638353|ref|XP_869341.1| PREDICTED: similar to methylmalonic aciduria type A isoform 2 [Bos taur...
194.0 [0..1] [295..123]
gi|187028896, gi... - gi|39582290|emb|CAE67539.1| Hypothetical protein CBG13064 [Caenorhabditis briggsae], gi|187028896|em...
192.0 [0..1] [298..1]
gi|114596301 - gi|114596301|ref|XP_526697.2| PREDICTED: methylmalonic aciduria type A [Pan troglodytes]
191.0 [0..1] [295..121]
MMAA_MOUSE - Methylmalonic aciduria type A homolog, mitochondrial OS=Mus musculus GN=Mmaa PE=1 SV=1
190.0 [0..1] [295..118]
gi|73978278 - gi|73978278|ref|XP_539752.2| PREDICTED: similar to methylmalonic aciduria type A [Canis familiaris]
190.0 [0..1] [295..584]
gi|68198080, gi|... - gi|68234307|ref|ZP_00573394.1| ArgK protein [Frankia sp. EAN1pec], gi|68198080|gb|EAN12365.1| ArgK p...
189.0 [0..2] [295..32]
gi|111224338, gi... - gi|111224338|ref|YP_715132.1| arginine/ornithine transport system ATPase [Frankia alni ACN14a], gi|1...
189.0 [0..2] [295..28]
MMAA - methylmalonic aciduria (cobalamin deficiency) cblA type
188.0 [0..1] [295..121]

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Predicted Domain #1
Region A:
Residues: [1-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLKMVLDEE REKYKKFGRD SMIFRVGISG SPGVGKSSFI EALGAELTEN RGKKVAVLTI  60
   61 DPTSAMTGGS VLGDLTRMQE LSRNPKAYIR QSPTSGSLGG VTRGIHEAVI LCEGAGYDIV 120
  121 IIETVGVGQS ETSVSDMCDM MCLLLSPAHG DELQGVKRGI MEMSDLLVVT KDDGDLKAKA 180
  181 KMTQAEYISA LKFMRPRLDV WRPKVMRSSI MDKESVSEVC SSLYEFWDTI GESGDLERRR 240
  241 QDQMKKWMWN HVKDEIMSVF QKHPKIAHLA PKLENEIRSG KITPGLAAET MIRTFFGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.30103
Match: 2qm7A
Description: No description for 2qm7A was found.

Predicted functions:

Term Confidence Notes
amino acid transmembrane transporter activity 2.01505980789636 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.95073642969863 bayes_pls_golite062009
pyrophosphatase activity 1.91141407779641 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.9017593265179 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.90014393273511 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.82370030183942 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.79922369980544 bayes_pls_golite062009
transporter activity 1.55572428045529 bayes_pls_golite062009
ATPase activity 1.48474288797022 bayes_pls_golite062009
amine transmembrane transporter activity 1.46279910519982 bayes_pls_golite062009
transmembrane transporter activity 1.38483976298883 bayes_pls_golite062009
ATPase activity, coupled 1.37457738689583 bayes_pls_golite062009
active transmembrane transporter activity 1.24278046928678 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.2014318795788 bayes_pls_golite062009
primary active transmembrane transporter activity 1.19670408144267 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1.17063957238561 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 1.16918853509059 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 1.16885789920943 bayes_pls_golite062009
hydrolase activity 1.09839981963412 bayes_pls_golite062009
binding 0.855534295206446 bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity 0.659246448488891 bayes_pls_golite062009
catalytic activity 0.605053499033488 bayes_pls_golite062009
purine ribonucleotide binding 0.5127850474754 bayes_pls_golite062009
ribonucleotide binding 0.51230334374838 bayes_pls_golite062009
purine nucleotide binding 0.50688037036449 bayes_pls_golite062009
nucleotide binding 0.49473184426584 bayes_pls_golite062009
amine-transporting ATPase activity 0.42499798704757 bayes_pls_golite062009
amino acid-transporting ATPase activity 0.40666423730781 bayes_pls_golite062009
substrate-specific transporter activity 0.0838665746103899 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle