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View Structure Prediction Details

Protein: ldh-1
Organism: Caenorhabditis elegans
Length: 333 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ldh-1.

Description E-value Query
Range
Subject
Range
gi|67968888 - gi|67968888|dbj|BAE00801.1| unnamed protein product [Macaca fascicularis]
gi|109107092 - gi|109107092|ref|XP_001084747.1| PREDICTED: lactate dehydrogenase A isoform 6 [Macaca mulatta]
381.0 [0..1] [331..30]

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Predicted Domain #1
Region A:
Residues: [1-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTIKEVFA EIAAPVENSH GKVTVVGVGQ VGMACAYSIL QQNLANELCL VDVVADKLKG  60
   61 EMMDLQHGLA FTRHCTVKAD TDYSITAGSK LCVVTAGARQ REGETRLSLV QRNVEIFKGI 120
  121 IPQLVKYSPD TCILVVSNPV DVLTYVTWKL SGLPRERVFG SGTNLDSARF RFLLSEKLNI 180
  181 APSSCHGWII GEHGDSSVAV WSGVNVAGVT LHEIKPDIGE KTDNEHWEAE IHKKVVDSAY 240
  241 EIIKLKGYTS WAIGLSVAKI AQGIFSNSRN VFALSTNVKG FHGINDDVYL SLPVVLGSAG 300
  301 LTHVVKQQLT EAEVQKLHNS AKALLEVQNG IVM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1i10A
Description: Lactate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-lactate dehydrogenase activity 2.59062377380589 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 1.27032644348698 bayes_pls_golite062009
retinol dehydrogenase activity 1.16811519855038 bayes_pls_golite062009
binding 0.982999356179965 bayes_pls_golite062009
oxidoreductase activity 0.9367410227151 bayes_pls_golite062009
NAD or NADH binding 0.74536049628503 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.729242797855749 bayes_pls_golite062009
fatty acid synthase activity 0.714637370305282 bayes_pls_golite062009
DNA binding 0.525227236870065 bayes_pls_golite062009
protein binding 0.507836099271263 bayes_pls_golite062009
nucleic acid binding 0.459537641913493 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.418775403210681 bayes_pls_golite062009
coenzyme binding 0.35922330382799 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.32207755075663 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.192594057004213 bayes_pls_golite062009
transcription regulator activity 0.177044638410302 bayes_pls_golite062009
molecular transducer activity 0.0433763403499039 bayes_pls_golite062009
signal transducer activity 0.0433763403499039 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle