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View Structure Prediction Details

Protein: air1
Organism: Schizosaccharomyces pombe
Length: 313 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for air1.

Description E-value Query
Range
Subject
Range
gi|37496499 - gi|37496499|emb|CAD48455.1| gag-pol fusion polyprotein precursor [Human immunodeficiency virus 1]
195.0 [0..2] [313..300]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVSNQKAES DDGSDIDDAA LLQKINSLPI DQSITNSVSL EKHDFQGSDD HDSSTDLSDS  60
   61 TLEDVEGSEW ADVSRGRYFG SDPSES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.221849
Match: 1bajA
Description: HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.04588712677166 bayes_pls_golite062009
DNA binding 2.53317408686316 bayes_pls_golite062009
nucleic acid binding 2.33828046499668 bayes_pls_golite062009
binding 2.07015157850093 bayes_pls_golite062009
transcription factor activity 2.0090791129794 bayes_pls_golite062009
protein binding 1.30905787243512 bayes_pls_golite062009
transcription activator activity 0.68790059848359 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVCHNCKGNG HISKDCPHVL CTTCGAIDDH ISVRCPWTKK CMNCGLLGHI AARCSEPRKR  60
   61 GPRVCRTCHT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1aafA
Description: NUCLEOCAPSID ZINC FINGERS DETECTED IN RETROVIRUSES: EXAFS STUDIES ON INTACT VIRUSES AND THE SOLUTION-STATE STRUCTURE OF THE NUCLEOCAPSID PROTEIN FROM HIV-1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [157-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTHTSSTCPL IWRYYVEKEH PVRIDVSEVR KFCYNCASDE HFGDDCTLPS RSNYPEST

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.22
Match: 2cqfA
Description: Solution Structure of the Zinc-finger domain in LIN-28
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [215-313]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFCEANCPSG NDASNKEFFE TRRKEFQLER REQNRNQKSS KQRPFHKPGN SLASRLGSKP  60
   61 KSFKRKHSPP SEENGNLSFH SSDGRKFTKT SKKNRKRKW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2c55A
Description: Solution Structure of the Human Immunodeficiency Virus Type 1 p6 Protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle