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View Structure Prediction Details

Protein: seb1
Organism: Schizosaccharomyces pombe
Length: 620 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for seb1.

Description E-value Query
Range
Subject
Range
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
191.0 [0..216] [619..1]
gi|73976787 - gi|73976787|ref|XP_857499.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
190.0 [0..216] [617..1]
gi|42545054, gi|... - gi|46109084|ref|XP_381600.1| hypothetical protein FG01424.1 [Gibberella zeae PH-1], gi|42545054|gb|E...
189.0 [0..2] [608..3]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIAEFDGI LDSLEHSKTG ISGSKILKLT NLSMENVSEN AQFVASVYKY AKRAPVTHKL  60
   61 GALYILDSIV RSFQDGAKKN NESFENPVDA SFSGGWCKAA EITDSLVADA IQHAPSAHLP 120
  121 KILKLCDIWE KASTFPPEKL ESLRSKLKDA MASTEPVSVD SAAAPSQSTN PEGNGGSVGS 180
  181 QAAAPTSRPV ENDAASILEA LAAFAQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 2diwA
Description: No description for 2diwA was found.

Predicted Domain #2
Region A:
Residues: [208-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVPSAAEES VSTPPQPAVA PSVSAVVPNL PVHPATAINA QSQSGNPLSN PLFQPSNVPQ  60
   61 SIPSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMGMKTGSVN DTQSQQITLM NVLASQNVPP AQIDSIMKAA FPNYNAPFQP AGVGSVPLPA  60
   61 PTSSQSLRLG SLHRSRSPSP RSGRPRRSPS PSHLSIPSTL PPADGVPKPT PDGFPRRFER 120
  121 DPTIPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.50398990564944 bayes_pls_golite062009
RNA binding 4.46119712758726 bayes_pls_golite062009
binding 4.16717332578111 bayes_pls_golite062009
mRNA binding 3.05425904007847 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.73925834998328 bayes_pls_golite062009
1.52879236550095 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
single-stranded RNA binding 0.852368751354665 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
poly-pyrimidine tract binding 0.56829350502235 bayes_pls_golite062009
sequence-specific DNA binding 0.294937517750882 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [399-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSIKVYSRTL FLGGITRSVR EPVLRSMFER FGSVQSLILN HNYRHGFLKM FRRDAAEKAQ  60
   61 VAMENVPFAD TTIRTKWGVG FGPRECSDFS TGISVIPIRL LTDADRTWLV TAEYGGTGGL 120
  121 PITPGIALDE PDIEIGLGIS SKAISKRGKD FAMRRDERFR GRKPYRGGPP IHHGERHFDS 180
  181 GNDWHGNPST VPPPTNPYNP GYPYMDPNYS SGYVSQPPWQ PQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.50398990564944 bayes_pls_golite062009
RNA binding 4.46119712758726 bayes_pls_golite062009
binding 4.16717332578111 bayes_pls_golite062009
mRNA binding 3.05425904007847 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.73925834998328 bayes_pls_golite062009
1.52879236550095 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
single-stranded RNA binding 0.852368751354665 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
poly-pyrimidine tract binding 0.56829350502235 bayes_pls_golite062009
sequence-specific DNA binding 0.294937517750882 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle