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View Structure Prediction Details

Protein: seb1
Organism: Schizosaccharomyces pombe
Length: 620 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for seb1.

Description E-value Query
Range
Subject
Range
gi|76689285 - gi|76689285|ref|XP_881509.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
191.0 [0..216] [619..1]
gi|73976787 - gi|73976787|ref|XP_857499.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
190.0 [0..216] [617..1]
gi|42545054, gi|... - gi|46109084|ref|XP_381600.1| hypothetical protein FG01424.1 [Gibberella zeae PH-1], gi|42545054|gb|E...
189.0 [0..2] [608..3]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIAEFDGI LDSLEHSKTG ISGSKILKLT NLSMENVSEN AQFVASVYKY AKRAPVTHKL  60
   61 GALYILDSIV RSFQDGAKKN NESFENPVDA SFSGGWCKAA EITDSLVADA IQHAPSAHLP 120
  121 KILKLCDIWE KASTFPPEKL ESLRSKLKDA MASTEPVSVD SAAAPSQSTN PEGNGGSVGS 180
  181 QAAAPTSRPV ENDAASILEA LAAFAQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 2diwA
Description: No description for 2diwA was found.

Predicted Domain #2
Region A:
Residues: [208-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVPSAAEES VSTPPQPAVA PSVSAVVPNL PVHPATAINA QSQSGNPLSN PLFQPSNVPQ  60
   61 SIPSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMGMKTGSVN DTQSQQITLM NVLASQNVPP AQIDSIMKAA FPNYNAPFQP AGVGSVPLPA  60
   61 PTSSQSLRLG SLHRSRSPSP RSGRPRRSPS PSHLSIPSTL PPADGVPKPT PDGFPRRFER 120
  121 DPTIPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.50398990564944 bayes_pls_golite062009
RNA binding 4.46119712758726 bayes_pls_golite062009
binding 4.16717332578111 bayes_pls_golite062009
mRNA binding 3.05425904007847 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.73925834998328 bayes_pls_golite062009
1.52879236550095 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
single-stranded RNA binding 0.852368751354665 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
poly-pyrimidine tract binding 0.56829350502235 bayes_pls_golite062009
sequence-specific DNA binding 0.294937517750882 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [399-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSIKVYSRTL FLGGITRSVR EPVLRSMFER FGSVQSLILN HNYRHGFLKM FRRDAAEKAQ  60
   61 VAMENVPFAD TTIRTKWGVG FGPRECSDFS TGISVIPIRL LTDADRTWLV TAEYGGTGGL 120
  121 PITPGIALDE PDIEIGLGIS SKAISKRGKD FAMRRDERFR GRKPYRGGPP IHHGERHFDS 180
  181 GNDWHGNPST VPPPTNPYNP GYPYMDPNYS SGYVSQPPWQ PQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.50398990564944 bayes_pls_golite062009
RNA binding 4.46119712758726 bayes_pls_golite062009
binding 4.16717332578111 bayes_pls_golite062009
mRNA binding 3.05425904007847 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.73925834998328 bayes_pls_golite062009
1.52879236550095 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
single-stranded RNA binding 0.852368751354665 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
poly-pyrimidine tract binding 0.56829350502235 bayes_pls_golite062009
sequence-specific DNA binding 0.294937517750882 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle