YRC Public Data Repository - Protein Structure Prediction

Protein:	mug71
Organism:	Schizosaccharomyces pombe
Length:	606 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mug71.

Description	E-value	Query Range	Subject Range
gi\|54643068, gi\|... - gi\|54643068\|gb\|EAL31812.1\| GA13952-PA [Drosophila pseudoobscura], gi\|125981507\|ref\|XP_001354757.1\| G...	451.0	[0..1]	[530..1]
gi\|116116015, gi... - gi\|118793862\|ref\|XP_321119.3\| ENSANGP00000018453 [Anopheles gambiae str. PEST], gi\|116116015\|gb\|EAA0...	441.0	[0..1]	[530..1]
gi\|108874536, gi... - gi\|157123065\|ref\|XP_001653810.1\| hypothetical protein AaeL_AAEL009372 [Aedes aegypti], gi\|157123063\|...	431.0	[0..1]	[530..1]
gi\|50748366 - gi\|50748366\|ref\|XP_421214.1\| PREDICTED: similar to CG1578-PA [Gallus gallus]	423.0	[0..1]	[534..74]
gi\|91080353 - gi\|91080353\|ref\|XP_974763.1\| PREDICTED: hypothetical protein [Tribolium castaneum]	422.0	[0..1]	[532..1]
orf19.839 - orf19.839 CGDID:CAL0002720 Assembly 19, Contig19-10076 (100649, 98709) CDS, reverse complemented, tr... gi\|68469906, gi\|... - gi\|68469906\|ref\|XP_720963.1\| hypothetical protein CaO19.839 [Candida albicans SC5314], gi\|46442857\|g...	414.0	[0..1]	[526..20]
gi\|48101080 - gi\|48101080\|ref\|XP_395061.1\| PREDICTED: similar to ATP binding domain 4 [Apis mellifera]	414.0	[0..1]	[532..1]
gi\|49119549, gi\|... - gi\|49119549\|gb\|AAH73100.1\| MGC83562 protein [Xenopus laevis], gi\|148233008\|ref\|NP_001085655.1\| MGC83...	412.0	[0..1]	[534..1]
gi\|49077522, gi\|... - gi\|71021825\|ref\|XP_761143.1\| hypothetical protein UM04996.1 [Ustilago maydis 521], ref\|XP_402611.1\| ...	407.0	[0..1]	[553..1]
gi\|7547107, gi\|1... - gi\|7547107\|gb\|AAF63779.1\| unknown protein [Arabidopsis thaliana], gi\|15229304\|ref\|NP_187098.1\| endor...	402.0	[0..1]	[532..1]

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Predicted Domain #1

Region A:
Residues: [1-279]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLGLISGG KDSCFNLMHC VSLGHEVVAL ANLHPEDGKD EIDSFMYQSV GHDVIPLYAE  60
   61 CFDLPLYREK IGGQSINQNL DYQFTEKDET EDLYRLIKRV LTNHPDLEAV STGAILSTYQ 120
  121 RTRVENVCKR LGLKSLSFLW QKDQEKLLND MVVSGLNAIL IKVAAIGLTR KDLGKSLAEM 180
  181 QDKLLTLNKK FELHPCGEGG EYETLVLDCP LFKKRIVLTD KEVVEHSSGE VCYLKVKACV 240
  241 KDKPEWQPIS LKSELVPNEE LLGEEYSHIY HTISKKYEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.045757
Match:	2d13A
Description:	Crystal Structure of PH1257 from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity	2.99185607397345	bayes_pls_golite062009
nucleic acid binding	1.14663773925119	bayes_pls_golite062009
DNA binding	0.992954560970173	bayes_pls_golite062009
catalytic activity	0.828867994386867	bayes_pls_golite062009
binding	0.752095595503409	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [280-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDDQEETPTS LIPIPLRESA FQQKKGSFLV LGNVVATKGS YNTFQGEAES AINNLNELLG  60
   61 TYGYSNKNVY FVTVILSSMS KFAEFNSVYN KYFDFTNPPS RSCVAAPLAS EYRIVMSCIV 120
  121 GDVTE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.522879
Match:	1qd9A
Description:	Purine regulatory protein YabJ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	2.55513289511254	bayes_pls_golite062009
nuclease activity	1.95684086528131	bayes_pls_golite062009
endonuclease activity	1.93161199243014	bayes_pls_golite062009
binding	1.28584712198396	bayes_pls_golite062009
endoribonuclease activity	1.18839679198466	bayes_pls_golite062009
catalytic activity	1.00848565859536	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.659253495197665	bayes_pls_golite062009
hydrolase activity	0.213547115506972	bayes_pls_golite062009
protein binding	0.147266452718662	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [405-606]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRALHVQGQS YWAPANIGPY SQSICANGVV FISGQIGLIP SVMELKLHDK IFEMVLALQH  60
   61 ANRVAKAMRV GSLIACLAYV CDSRDADCVV KIWSEYTKNT GESSPVLVAL VDALPRNASV 120
  121 EWQLLYNDSS CDVPLLSSLV TNQTLFGSDT AWDVALLNQN GLRMESSFIH HEHPSAYAIV 180
  181 LNNAFPNSQL LHVRYTARDQ NV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.39794
Match:	2dyyA
Description:	No description for 2dyyA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: