YRC Public Data Repository - Protein Structure Prediction

Protein:	plg7
Organism:	Schizosaccharomyces pombe
Length:	438 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for plg7.

Description	E-value	Query Range	Subject Range
gi\|1314246, gi\|1... - gi\|31543410\|ref\|NP_005075.2\| phospholipase A2, group VII [Homo sapiens], gi\|23512331\|gb\|AAH38452.1\| ...	368.0	[0..1]	[433..46]
gi\|109071407 - gi\|109071407\|ref\|XP_001103358.1\| PREDICTED: phospholipase A2, group VII [Macaca mulatta]	367.0	[0..1]	[433..46]
PAFA_CANLF - Platelet-activating factor acetylhydrolase OS=Canis lupus familiaris GN=PLA2G7 PE=2 SV=1	367.0	[0..1]	[433..46]
gi\|114607670 - gi\|114607670\|ref\|XP_518519.2\| PREDICTED: phospholipase A2, group VII [Pan troglodytes]	366.0	[0..1]	[433..1]
PAFA_BOVIN - Platelet-activating factor acetylhydrolase OS=Bos taurus GN=PLA2G7 PE=2 SV=1	353.0	[0..1]	[433..46]
gi\|94402878, gi\|... - gi\|94402885\|ref\|XP_001003920.1\| PREDICTED: similar to phospholipase A2, group VII isoform 5 [Mus mus...	352.0	[0..1]	[433..45]
PAFA2_RAT - Platelet-activating factor acetylhydrolase 2, cytoplasmic OS=Rattus norvegicus GN=Pafah2 PE=1 SV=2	350.0	[0..1]	[432..1]

Back

Predicted Domain #1

Region A:
Residues: [1-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLGFSSKKQ LPAYCGPLPV GSLVLELSVP EEFRCEYKTI EHKLRTVKVR IFYPLDPTKD  60
   61 VEPRTDELWL PFHEGIPEVA KGFRWWLLRA FASGLTNLAL PVYKGELFHP PNNGKLPVFI 120
  121 FSHGLVGSRN VYSSLCGTIA SYGIVVLAME HRDNSAIIST VRDPLHPEEP PYVVQYREIS 180
  181 DFYADATVVL QNERLLFRQQ EIQIALQMIR NINDLGTPDE NLPFLCSVDS SFYNSVFQSM 240
  241 KGNLNTAQGE LIVAGHSFGA ATCAFISGSS TKSLYNDYMF HTEFKCSILY DIWMLPVRQL 300
  301 HLSTMRYPTL MIISYEFRRF VDNFQALESW LVNKDSENQN AGESADEKMS VVPLKKYSHV 360
  361 FVYDGTVHAN QSDLPILLPR MVLRVLKGKF EADPYEALRI NTRSSVQFLR ENHVENVQGD 420
  421 NDPSSLQTNI IPGWERIM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.154902
Match:	1jfrA
Description:	Lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carboxylesterase activity	2.10340684157921	bayes_pls_golite062009
phospholipase activity	1.98964694567462	bayes_pls_golite062009
lipase activity	1.95656432876646	bayes_pls_golite062009
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009
binding	0.978846093152455	bayes_pls_golite062009
peptidase activity	0.946698616106528	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.786172015267385	bayes_pls_golite062009
serine hydrolase activity	0.527527404338	bayes_pls_golite062009
acylglycerol lipase activity	0.345658974420231	bayes_pls_golite062009
serine-type peptidase activity	0.33062249657108	bayes_pls_golite062009
triglyceride lipase activity	0.05324087110088	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: