YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC959.04c
Organism:	Schizosaccharomyces pombe
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC959.04c.

Description	E-value	Query Range	Subject Range
KRE2_CANAL - Glycolipid 2-alpha-mannosyltransferase OS=Candida albicans GN=KRE2 PE=3 SV=1 gi\|238880609 - gi\|238880609\|gb\|EEQ44247.1\| alpha-1,2 mannosyltransferase KTR1 [Candida albicans WO-1] MNT1_CANAL - Glycolipid 2-alpha-mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNT1...	401.0	[0..5]	[297..114]
gi\|49654834 - gi\|49654834\|emb\|CAG87338.1\| DEHA2D15708p [Debaryomyces hansenii] gi\|49654834, gi\|... - gi\|50421243\|ref\|XP_459167.1\| hypothetical protein DEHA0D17105g [Debaryomyces hansenii CBS767], gi\|49...	398.0	[0..5]	[297..102]
gi\|44985528 - gi\|44985528\|gb\|AAS54224.1\| AGL267Cp [Ashbya gossypii ATCC 10895] gi\|45200830, gi\|... - gi\|45200830\|ref\|NP_986400.1\| AGL267Cp [Ashbya gossypii ATCC 10895], gi\|44985528\|gb\|AAS54224.1\| AGL26...	396.0	[0..5]	[297..113]
KTR3 - Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of ... KTR3_YEAST - Probable mannosyltransferase KTR3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTR3 P... gi\|151946594 - gi\|151946594\|gb\|EDN64816.1\| kre2-related protein [Saccharomyces cerevisiae YJM789]	395.0	[0..4]	[297..90]
gi\|1362240 - gi\|1362240\|pir\|\|S57713 probable mannosyl transferase - yeast (Candida albicans)	391.0	[0..5]	[297..145]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYFLILFSSN AELGEVLRTM RSVEDRFNKR FHYPWTFYGM DEFTEYFMST TSTIASGHCE  60
   61 YGTKGITYTN HLQFILTISY LVHWDLSQVK PLVENNRLYQ QRADALAQEN LSYVYSPLFH 120
  121 SFQDWVVRSL LYHPQLEYDY VWRIEPGLKL VCEEKKDIFS TFKDSDIVFT NHVCERKHSG 180
  181 IYAMEEAIEE YKILNTQGDF SNIWVYSNNY TYCKYWPFNE ILSLKQIRHN QTYTNLINYL 240
  241 LGSGGTYYHR WTESDILSAA FGVLRARANH MESVGFFLND DVHYCPETIP YTGRCACL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1s4nA
Description:	Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
mannosyltransferase activity	3.87594044828967	bayes_pls_golite062009
transferase activity	3.32517438937547	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.70047942699289	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.51696952719873	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.33861720107822	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity	1.53617752123292	bayes_pls_golite062009
nucleotidyltransferase activity	1.36890882280676	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.33788133706753	bayes_pls_golite062009
uridylyltransferase activity	1.27888067902271	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	1.10309252319727	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.897978517422275	bayes_pls_golite062009
binding	0.503732110578643	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: