YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAPB8E5.04c
Organism:	Schizosaccharomyces pombe
Length:	188 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAPB8E5.04c.

Description	E-value	Query Range	Subject Range
gi\|39951829, gi\|... - gi\|39951829\|ref\|XP_363631.1\| hypothetical protein MG01557.4 [Magnaporthe grisea 70-15], gb\|EAA55906....	243.0	[0..1]	[176..79]
NPC2_MAGO7 - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Magnaporthe oryzae (strain 70-15 / ATC... NPC2_MAGGR - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Magnaporthe grisea GN=NPC2 PE=3 SV=2	238.0	[0..1]	[176..1]
NPC2_ASHGO - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Ashbya gossypii (strain ATCC 10895 / C... NPC2_ASHGO - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Ashbya gossypii GN=NPC2 PE=3 SV=1	233.0	[0..17]	[176..10]
NPC2_NEUCR - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Neurospora crassa (strain ATCC 24698 /... NPC2_NEUCR - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Neurospora crassa GN=npc-2 PE=3 SV=1	231.0	[0..1]	[176..1]
gi\|42554300, gi\|... - gi\|46136141\|ref\|XP_389762.1\| hypothetical protein FG09586.1 [Gibberella zeae PH-1], gi\|42554300\|gb\|E...	230.0	[0..1]	[177..1]
NPC2_ASPOR - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Aspergillus oryzae (strain ATCC 42149 ... gi\|220694311, gi... - gi\|238496391\|ref\|XP_002379431.1\| ML domain protein, putative [Aspergillus flavus NRRL3357], gi\|22069... NPC2_ASPOR - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Aspergillus oryzae GN=pltp PE=1 SV=1	222.0	[0..3]	[178..4]
NPC2_CANAL - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Candida albicans (strain SC5314 / ATCC... NPC2_CANAL - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Candida albicans GN=NPC2 PE=3 SV=1	221.0	[0..7]	[176..27]
NPC2_EMENI - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Emericella nidulans (strain FGSC A4 / ... NPC2_EMENI - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Emericella nidulans GN=npc2 PE=3 SV=1	220.0	[0..3]	[176..4]
gi\|159129536 - gi\|159129536\|gb\|EDP54650.1\| ML domain protein, putative [Aspergillus fumigatus A1163] gi\|66853105, gi\|... - gi\|71001572\|ref\|XP_755467.1\| ML domain protein [Aspergillus fumigatus Af293], gi\|66853105\|gb\|EAL9342...	202.0	[0..1]	[172..74]
NPC2_ASPFU - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Aspergillus fumigatus GN=npc2 PE=3 SV=... NPC2_ASPFU - Phosphatidylglycerol/phosphatidylinositol transfer protein OS=Neosartorya fumigata (strain ATCC MYA-...	199.0	[0..1]	[172..1]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLTTFIYAI TCLPIFISAS SWFSSFSFGE SKSTDLVSST SEKIPGANPA SYCADWDRGD  60
   61 DHVVVDYINL IPNPPAAGKN LTIETEINVG TTVLNGSYVD IQVKYGFVRI VNERLDICDK 120
  121 AYELAAVECP VEPGIITKQA TISLPWAIPP GRYHVLATAY NADGEQLTCV SASVSFSHFG 180
  181 FQLINQDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.30103
Match:	1pu5A
Description:	GM2-activator Protein crystal structure
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lipid transporter activity	2.41372192504662	bayes_pls_golite062009
beta-N-acetylgalactosaminidase activity	1.34560319562268	bayes_pls_golite062009
hydrolase activity	1.29194618858109	bayes_pls_golite062009
binding	1.09172804348449	bayes_pls_golite062009
lipid binding	0.871648239018759	bayes_pls_golite062009
beta-N-acetylhexosaminidase activity	0.467838114456119	bayes_pls_golite062009
transporter activity	0.433212475678148	bayes_pls_golite062009
lipase activator activity	0.366397482303317	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	0.318751423502705	bayes_pls_golite062009
hexosaminidase activity	0.242981768893225	bayes_pls_golite062009
enzyme regulator activity	0.170040495989689	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: