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View Structure Prediction Details

Protein: SPBC30B4.02c
Organism: Schizosaccharomyces pombe
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC30B4.02c.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
415.0 [0..37] [585..1819]
gi|50757613 - gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy chain [Gallus gallus]
323.0 [0..37] [558..766]
gi|3668187 - gi|3668187|dbj|BAA33452.1| myosin heavy chain [Theragra chalcogramma]
293.0 [0..37] [508..817]
gi|73955710 - gi|73955710|ref|XP_850299.1| PREDICTED: similar to myosin, heavy polypeptide 13, skeletal muscle iso...
285.0 [0..37] [540..819]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
282.0 [0..37] [558..822]
gi|47205359 - gi|47205359|emb|CAF96150.1| unnamed protein product [Tetraodon nigroviridis]
268.0 [0..37] [555..762]
gi|76643955 - gi|76643955|ref|XP_882593.1| PREDICTED: similar to Myosin-8 (Myosin heavy chain, skeletal muscle, pe...
264.0 [0..37] [558..818]

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Predicted Domain #1
Region A:
Residues: [1-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNFDDLQIL DQLQTSARFR GDTRIRRFKG SNNSKSPFGL NPSSRISQWP RITFIRAKDN  60
   61 YNPAEELCQL IDEQNAHNEA KHQSKEIMLP KETNVKSCED LSKTGEIKAL DIVLFKAITS 120
  121 KGDTLKVKKI PEYAEAFDTT KNVEVSSFPE KSMNENVLIQ HSLNLAPSDK EISSTEESEQ 180
  181 LCYKEQESEK ELYSKDNDDS LDILNVPNLV NDDIANNNAA PPPPLAQAQE QLSTENEDEF 240
  241 DIDDTTDKMT TFTMNKFADL SVLEEDDDDE DEDEELEGEK EEEEEEKEKP EISNYDETEG 300
  301 KVNFSLEDSE SLEFDEGSDD YDYAKLTTEL VGNTDSLAED EDDILEEDED EDEEELLAIF 360
  361 DASDDSEIEA YLSIGDTLQN DFTIYDYDSE DEEYNNPSTQ KTEKVSQSKK GAKVKEEKGL 420
  421 KKDRKLPKKM RKAQKKLERK AGKAVAARMG DAFSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [456-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLDDESMNLY AELQEQWLKD KSKKARRRAE REKLRSEGLL GKKSKKKLLR ESQKPSSSDS  60
   61 DNASLTRIDK IFINDVYQRM QQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [538-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKHSAIEEIS LPPCRKYVRR LVHALANDLN LKSRSYGSGN KRYTMLSKTH K

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.5
Match: 1mszA
Description: SmuBP-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.859940889466509 bayes_pls_golite062009
nucleic acid binding 0.598402461163598 bayes_pls_golite062009
DNA binding 0.545141938793193 bayes_pls_golite062009
transcription regulator activity 0.360465698090476 bayes_pls_golite062009
catalytic activity 0.307971467423079 bayes_pls_golite062009
protein binding 0.0446628977860376 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [589-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDASSVDLVS LTRIMERLQT RVEYQSFSKS GRKSRMTVSS VRSSKATRVY DGQIVGEDAP  60
   61 EISKENPGRR LLEKLGWYAG KGLGHPENEG SKDSLRAIVK VSRSGLG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle