YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC970.08
Organism:	Schizosaccharomyces pombe
Length:	967 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC970.08.

Description	E-value	Query Range	Subject Range
gi\|151942005 - gi\|151942005\|gb\|EDN60361.1\| inositol polyphosphate kinase [Saccharomyces cerevisiae YJM789] KCS1 - Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high ener... KCS1_YEAST - Inositol hexakisphosphate kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KCS1 ...	660.0	[0..115]	[966..76]
gi\|46109530, gi\|... - gi\|46109530\|ref\|XP_381823.1\| hypothetical protein FG01647.1 [Gibberella zeae PH-1], gi\|42545505\|gb\|E...	637.0	[0..21]	[931..480]
gi\|18376053, gi\|... - gi\|32404382\|ref\|XP_322804.1\| hypothetical protein [Neurospora crassa], gi\|28917903\|gb\|EAA27589.1\| pr... gi\|85081967 - gi\|85081967\|ref\|XP_956825.1\| hypothetical protein NCU03546 [Neurospora crassa OR74A]	618.0	[0..26]	[931..461]
gi\|67541420, gi\|... - gi\|67541420\|ref\|XP_664484.1\| hypothetical protein AN6880.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	606.0	[0..33]	[937..306]
gi\|44980630, gi\|... - gi\|45185009\|ref\|NP_982727.1\| AAR184Wp [Ashbya gossypii ATCC 10895], gi\|44980630\|gb\|AAS50551.1\| AAR18... gi\|44980630 - gi\|44980630\|gb\|AAS50551.1\| AAR184Wp [Ashbya gossypii ATCC 10895]	524.0	[0..111]	[961..2]
gi\|115399552, gi... - gi\|115399552\|ref\|XP_001215365.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	442.0	[0..32]	[943..347]
gi\|66850966, gi\|... - gi\|70997151\|ref\|XP_753330.1\| inositol hexaphosphate kinase KCS1 [Aspergillus fumigatus Af293], gi\|66... gi\|159126945 - gi\|159126945\|gb\|EDP52061.1\| inositol hexaphosphate kinase KCS1, putative [Aspergillus fumigatus A116...	437.0	[0..69]	[943..376]
gi\|116200143, gi... - gi\|88179506\|gb\|EAQ86974.1\| hypothetical protein CHGG_08227 [Chaetomium globosum CBS 148.51], gi\|1162...	436.0	[0..70]	[929..368]
gi\|169779411 - gi\|169779411\|ref\|XP_001824170.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83772909 - gi\|83772909\|dbj\|BAE63037.1\| unnamed protein product [Aspergillus oryzae]	422.0	[0..63]	[943..7]
gi\|49524910, gi\|... - gi\|50286353\|ref\|XP_445605.1\| unnamed protein product [Candida glabrata], gi\|49524910\|emb\|CAG58516.1\|... gi\|49524910\|emb\|... - unnamed protein product [Candida glabrata CBS 138]	393.0	[0..296]	[961..355]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNAPKCYLP NSRKGRDVNF HDRGPETLKC LYDESEDNNN FTMHSESIGP KSLDSLSPRR  60
   61 LSNYSSAVDP RTTSLEDVPR LILTRSNSQE QTPLRTHTPV EYMSDSIHKS LADLQLGGSS 120
  121 YSVAESPV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [129-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVLQSSAVSE ADDMASAHSA HPSRKASRSL RLFESSTSNN LETGNSTNTA LHNVSSPLES  60
   61 VSERLSKSGS PSVGAQHDLD EVISEKDTSL SRRSSRGRSS APKRRKDSGS SKTTATYIPH 120
  121 NPSKKSSQHL PLLPDASFEL ERSVSRSYQS PASTPRSSVS SVSSSPPED

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [298-656]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPFFHWNVDY PVTVRLEPFK HQVGGHTAFF RFSKRAVCKP LTRNENTFYE TIEACHPELL  60
   61 PFIPKYIGVL NVTHTITKTE ENDSTTEYVN TESSSKTPAP HKHTFNSCYQ KKDYGYIPEV 120
  121 SVEQNRHIFP EWMLPDKRSH SYGSPKSLHH KSSSAGERPV SPTFVADIPP KTPWGTTLIN 180
  181 RKLREEVLRE VFAPKHARRR LGTRFHSRSS HRPSVFRDNS VAFGQLDNGN TSSRARDKDA 240
  241 DPNKSLSCSV EDKHYDLHSA VAEENEEVDE ELLNVPSNNQ GKSYRRFSSD AVWEEPESNE 300
  301 FPRVSGTMED YDSRESTGHT IKELRSTPNS HGTVPDDSIF AMDNEENSEL PPPLEPAEI

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.34
Match:	2iewA
Description:	No description for 2iewA was found.

Predicted Domain #4

Region A:
Residues: [657-967]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDPFRSVNDP RRVLSLPHMA SADEDHRIPA SDNQNNNNND ANALAENSES QHSTQIERYI  60
   61 VIEDLTSGMK RPCVLDVKMG TRQYGIMATE KKKASQTKKC AMTTSRVLGV RICGMQVWHP 120
  121 WLQSYTFEDK YVGRDIKAGE EFQHALMRYL GKTDDDEDNS HLLVHHIPTI IRKLEQLEQI 180
  181 VRFLKGSRLY ASSLLFLYDG EPPPSDKSSK EKVKPREIDI RIVDFANCVF AEDKELLAKA 240
  241 TCPPQHKDTY DRGYVRGLRT LRLYFLKIWK EAKGMQIAER GYEDSLSNAY DELGGLMSYS 300
  301 NDDDSCGETS T

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.522879
Match:	1tzdA
Description:	CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphotransferase activity, alcohol group as acceptor	3.30649735028428	bayes_pls_golite062009
kinase activity	3.15938216228549	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.81005558216959	bayes_pls_golite062009
inositol or phosphatidylinositol kinase activity	2.44446440066426	bayes_pls_golite062009
inositol trisphosphate 3-kinase activity	1.96891072919415	bayes_pls_golite062009
inositol trisphosphate kinase activity	1.96891072919415	bayes_pls_golite062009
transferase activity	1.91167919290181	bayes_pls_golite062009
catalytic activity	1.87792712964225	bayes_pls_golite062009
lipid kinase activity	1.58125486544697	bayes_pls_golite062009
binding	1.02604095388529	bayes_pls_golite062009
phosphatidylinositol phosphate kinase activity	0.449746940435062	bayes_pls_golite062009
ligase activity	0.435608917599349	bayes_pls_golite062009
protein kinase activity	0.422676745032915	bayes_pls_golite062009
protein binding	0.382966234080422	bayes_pls_golite062009
protein serine/threonine kinase activity	0.189737258618863	bayes_pls_golite062009
acid-amino acid ligase activity	0.14608192065514	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: