YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC13B11.03c
Organism:	Schizosaccharomyces pombe
Length:	256 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC13B11.03c.

Description	E-value	Query Range	Subject Range
gi\|39946066, gi\|... - gi\|39946066\|ref\|XP_362570.1\| hypothetical protein MG08153.4 [Magnaporthe grisea 70-15], gb\|EAA57184....	220.0	[0..2]	[254..484]
gi\|115387325, gi... - gi\|115387325\|ref\|XP_001211168.1\| hypothetical protein ATEG_01990 [Aspergillus terreus NIH2624], gi\|1...	219.0	[0..11]	[254..463]
gi\|83772861 - gi\|83772861\|dbj\|BAE62989.1\| unnamed protein product [Aspergillus oryzae] gi\|169779315 - gi\|169779315\|ref\|XP_001824122.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|220692964, gi... - gi\|238499953\|ref\|XP_002381211.1\| hydroxyacylglutathione hydrolase, putative [Aspergillus flavus NRRL...	218.0	[0..3]	[254..1]
GLO21_SCHPO - Probable hydroxyacylglutathione hydrolase C824.07 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24... SPAC824.07 - hydroxyacylglutathione hydrolase	208.0	[0..1]	[254..1]
gi\|28922635, gi\|... - gi\|32404876\|ref\|XP_323051.1\| hypothetical protein ( (AL513443) probable hydroxyacylglutathione hydro... gi\|85101167 - gi\|85101167\|ref\|XP_961096.1\| hypothetical protein ( (AL513443) probable hydroxyacylglutathione hydro...	207.0	[0..1]	[254..1]
GLO2_SYNJB - Hydroxyacylglutathione hydrolase OS=Synechococcus sp. (strain JA-2-3B'a(2-13)) GN=gloB PE=3 SV=1 gi\|86607653 - gi\|86607653\|ref\|YP_476415.1\| glyoxalase II family protein [Cyanobacteria bacterium Yellowstone B-Pri...	203.0	[0..3]	[255..1]
gi\|86605820 - gi\|86605820\|ref\|YP_474583.1\| glyoxalase II family protein [Cyanobacteria bacterium Yellowstone A-Pri... GLO2_SYNJA - Hydroxyacylglutathione hydrolase OS=Synechococcus sp. (strain JA-3-3Ab) GN=gloB PE=3 SV=1	202.0	[0..3]	[255..1]
gi\|115891513, gi... - gi\|115949376\|ref\|XP_001191822.1\| PREDICTED: similar to hydroxyacyl glutathione hydrolase [Strongyloc...	201.0	[0..1]	[254..1]
gi\|30684920 - gi\|30684920\|ref\|NP_850166.1\| GLX2-5 (GLYOXALASE 2-5); hydroxyacylglutathione hydrolase/ iron ion bin...	199.0	[0..2]	[254..69]

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Predicted Domain #1

Region A:
Residues: [1-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQILPIPM WVGTQDNYAY LLLCEETRQA AIVDPAEVNV VMPILKKKLK NKEIDLQAIL  60
   61 TTHHHADHSG GNLNLKKEFP HVTIYGGSDQ NGVSHVLQDK ETLRIGNVQI EALHTPCHTR 120
  121 DSICFYAHSS NEHAVFTGDT LFNAGCGRFF EGTAAEMHIA LNAVLSSLPN NTVIYPGHEY 180
  181 TKSNVKFASK HLQSEALNHL EGLCNHNQFI AGHITMGQEK QFNPFMRVTD PELQKHLGLN 240
  241 DPIKVMDELR TLKNQG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.221849
Match:	1qh3A
Description:	Glyoxalase II (hydroxyacylglutathione hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydroxyacylglutathione hydrolase activity	3.53012507604564	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009
binding	0.900972948435178	bayes_pls_golite062009
thiolester hydrolase activity	0.802604883362264	bayes_pls_golite062009
hydrolase activity	0.021392930321391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: