YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC1672.09
Organism:	Schizosaccharomyces pombe
Length:	467 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1672.09.

Description	E-value	Query Range	Subject Range
gi\|67537028, gi\|... - gi\|67537028\|ref\|XP_662288.1\| hypothetical protein AN4684.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	262.0	[0..1]	[444..1]
gi\|85113362 - gi\|85113362\|ref\|XP_964507.1\| hypothetical protein [Neurospora crassa OR74A] gi\|32417720, gi\|... - gi\|32417720\|ref\|XP_329338.1\| hypothetical protein [Neurospora crassa], gi\|28926292\|gb\|EAA35271.1\| hy...	261.0	[0..4]	[455..3]
gi\|88182320, gi\|... - gi\|88182320\|gb\|EAQ89788.1\| hypothetical protein CHGG_06407 [Chaetomium globosum CBS 148.51], gi\|1161...	256.0	[0..4]	[459..3]
gi\|110628931 - gi\|110628931\|gb\|ABG79930.1\| triacylglycerol lipase [Magnaporthe grisea]	252.0	[0..4]	[460..3]
gi\|114631717 - gi\|114631717\|ref\|XP_001138639.1\| PREDICTED: lipase-like, ab-hydrolase domain containing 2 [Pan trogl...	246.0	[0..74]	[442..143]
gi\|169780662 - gi\|169780662\|ref\|XP_001824795.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238505148, gi... - gi\|238505148\|ref\|XP_002383803.1\| triglyceride lipase-cholesterol esterase, putative [Aspergillus fla... gi\|83773535 - gi\|83773535\|dbj\|BAE63662.1\| unnamed protein product [Aspergillus oryzae]	245.0	[0..1]	[439..1]
gi\|114191415, gi... - gi\|115400321\|ref\|XP_001215749.1\| hypothetical protein ATEG_06571 [Aspergillus terreus NIH2624], gi\|1...	244.0	[0..1]	[439..1]
Lip4-PA - The gene Lipase 4 is referred to in FlyBase by the symbol Dmel\Lip4 (CG6113, FBgn0032264). It is a p... gi\|220947950, gi... - gi\|220957240\|gb\|ACL91163.1\| Lip4-PA [synthetic construct], gi\|220947950\|gb\|ACL86518.1\| Lip4-PA [synt...	244.0	[0..17]	[441..5]
LIPK_MOUSE - Lipase member K OS=Mus musculus GN=Lipk PE=2 SV=1	242.0	[0..73]	[442..26]
gi\|89033529 - gi\|89033529\|ref\|XP_942300.1\| PREDICTED: similar to lipase-like, ab-hydrolase domain containing 2 [Ho...	241.0	[0..74]	[442..28]

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Predicted Domain #1

Region A:
Residues: [1-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQLPFIQRL KWEEYMALFL GFFFVIFEKL LSCLAFMIHN TLGLFYRSVV RNEIKKRSKK  60
   61 RSRSRSVSLQ RAKAIHDAAD IREMCKISGY YVEDHLVRTE DDYILCIHRI SKDSPGRIGS 120
  121 PHPKKLPVVY CHHGLLMNSE VWVCNVDPRN CLVFDLVNKG YDVWLGNNRG NKYSRQHLRF 180
  181 DSTDKEFWDF SIDDFAQYDI PDTIDYILKT SGQTKLTYIG FSQGTAQAFA SLSIHPLLND 240
  241 KINSLIALAP AISPKGLHNR VVDAFVKARP SILFFLFGRK SILPSAGFWQ SFLAPKFFDA 300
  301 VLAYCLSQLF NWSCQNISSY QRLVSFAHLY SYTSVKCLVH WFQIMRSAEF RMYDNDQLGH 360
  361 DYFLKYYKAA KFPTNNIRTP IYLIWGGSDS LVDIQAMLNA LPAEVEHVKV DSYEHLDMIW 420
  421 ADTVKDYVIP PVLRRLRDIH HPPEHEENDK ENREIQKNHI APRNKPI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.30103
Match:	1hlgA
Description:	Gastric lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.20549979663539	bayes_pls_golite062009
malate dehydrogenase activity	2.28093794718528	bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity	2.14423515928317	bayes_pls_golite062009
palmitoyl-CoA hydrolase activity	1.62335985481548	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
triglyceride lipase activity	1.2959733599348	bayes_pls_golite062009
sterol esterase activity	1.21262745914703	bayes_pls_golite062009
thiolester hydrolase activity	1.18565704009692	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.985235528680562	bayes_pls_golite062009
peptidase activity	0.858311047004898	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.590445773074315	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.35429970866093	bayes_pls_golite062009
binding	0.351031277062254	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: