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View Structure Prediction Details

Protein: erf1
Organism: Schizosaccharomyces pombe
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for erf1.

Description E-value Query
Range
Subject
Range
gi|73970884, gi|... - gi|73978637|ref|XP_859950.1| PREDICTED: similar to eukaryotic translation termination factor 1 (pred...
452.0 [0..2] [388..19]
gi|31880783 - gi|31880783|ref|NP_057030.3| pelota homolog [Homo sapiens]
452.0 [0..1] [386..1]
PELO_PONPY - Protein pelota homolog - Pongo pygmaeus (Orangutan)
PELO_PONAB - Protein pelota homolog OS=Pongo abelii GN=PELO PE=2 SV=1
451.0 [0..1] [386..1]
PELO_BOVIN - (Q58DV0) Protein pelota homolog
451.0 [0..1] [388..1]
PELO_RAT - Protein pelota homolog OS=Rattus norvegicus GN=Pelo PE=1 SV=1
448.0 [0..1] [386..1]
PELO_MOUSE - Protein pelota homolog OS=Mus musculus GN=Pelo PE=2 SV=2
448.0 [0..1] [386..1]

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Predicted Domain #1
Region A:
Residues: [1-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLIQKNIEK NGSGWITMCP EEPEDMWHLY NILQVGDQLK ASTVRRVVKV GATGSTSGSR  60
   61 VVMKLRILVE NMDFDTKAAQ LHIKGRTTEY HPEVKMGSYH TLDLELHRNF TLYKNEWDAF 120
  121 ALDRVDAACN PSRNAEIGAV VLDEGLANIC LITDYMTILR QRIDQVIPRK RRGDSSAYQK 180
  181 GLDKFYDSVF QSINSEFDFD KLKVVILASP GFVARGLYDY IFSMAVKLDL KQIVKSKNKF 240
  241 VILHSSTGHI HSLNEILKDP AVESKLADTK YVQEIRVLNK FYDVMNEDDR KAWYGPNHVL 300
  301 KAFELGAIGE LLISDSLFRS SDIATRKKWV SLVEGVKEIN CPVYIFSSLH ESGKQLDLLS 360
  361 GIAAILTYPV DEEDISEDEE DEESQNFEHS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 124.0
Match: 1dt9A
Description: Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.8176240743328 bayes_pls_golite062009
translation release factor activity 3.48975835887408 bayes_pls_golite062009
translation termination factor activity 3.46050614877315 bayes_pls_golite062009
structural constituent of ribosome 2.50763528378297 bayes_pls_golite062009
binding 2.24516466558786 bayes_pls_golite062009
structural molecule activity 2.17996532926344 bayes_pls_golite062009
nucleic acid binding 2.09371417164502 bayes_pls_golite062009
translation regulator activity 1.83257472130927 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.81472167858216 bayes_pls_golite062009
mRNA binding 1.38466459724533 bayes_pls_golite062009
1.36644447800624 bayes_pls_golite062009
ribonuclease activity 0.519765773143644 bayes_pls_golite062009
protein binding 0.381324299701367 bayes_pls_golite062009
hydrolase activity 0.341035995293011 bayes_pls_golite062009
catalytic activity 0.264002643439785 bayes_pls_golite062009

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