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View Structure Prediction Details

Protein: rpn9
Organism: Schizosaccharomyces pombe
Length: 381 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpn9.

Description E-value Query
Range
Subject
Range
gi|28921249, gi|... - gi|32421413|ref|XP_331150.1| hypothetical protein [Neurospora crassa], gi|28921249|gb|EAA30559.1| hy...
gi|85093952 - gi|85093952|ref|XP_959795.1| hypothetical protein NCU02374 [Neurospora crassa OR74A]
365.0 [0..8] [380..5]
gi|39942888, gi|... - gi|39942888|ref|XP_360981.1| hypothetical protein MGG_03524 [Magnaporthe grisea 70-15], gb|EAA51929....
360.0 [0..8] [380..5]
gi|46127157, gi|... - gi|46127157|ref|XP_388132.1| hypothetical protein FG07956.1 [Gibberella zeae PH-1], gi|42553730|gb|E...
356.0 [0..9] [380..6]
gi|116179564, gi... - gi|88184707|gb|EAQ92175.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi|11617...
356.0 [0..8] [380..5]
gi|27803051, gi|... - gi|27803051|emb|CAD60754.1| unnamed protein product [Podospora anserina], gi|188219294|emb|CAP49274....
gi|189091882 - gi|189091882|ref|XP_001929774.1| [Podospora anserina]
354.0 [0..8] [380..5]
gi|159124726 - gi|159124726|gb|EDP49844.1| proteasome regulatory particle subunit (RpnI), putative [Aspergillus fum...
gi|70992613, gi|... - gi|70992613|ref|XP_751155.1| proteasome regulatory particle subunit (RpnI) [Aspergillus fumigatus Af...
352.0 [0..7] [380..28]
gi|40740734, gi|... - gi|67526517|ref|XP_661320.1| hypothetical protein AN3716.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
349.0 [0..7] [380..4]
gi|83767441 - gi|83767441|dbj|BAE57580.1| unnamed protein product [Aspergillus oryzae]
gi|169770225 - gi|169770225|ref|XP_001819582.1| hypothetical protein [Aspergillus oryzae RIB40]
343.0 [0..7] [380..4]
gi|115389972, gi... - gi|115389972|ref|XP_001212491.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
340.0 [0..7] [371..4]
gi|119194689, gi... - gi|90306734|gb|EAS36365.1| hypothetical protein CIMG_01719 [Coccidioides immitis RS], gi|119194689|r...
339.0 [0..8] [381..5]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTEMSVNMS DFLHDQATRA PESLQQSYIL MEDLYERKLW KQLTDALIVF FDTPETVPLR  60
   61 LPLYTNFVNS FRPNINQLKA VYMGLKAFES CSNDEALRNL NQIVNELDEE KYKDAYVYSI 120
  121 VAIARIKLIS GKLDEARELL VKASKIIDHI DYVESLIHSS YYSVSADYYK AKADYAQYYR 180
  181 HCLLY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.915 0.132 cytosol a.118.9 ENTH/VHS domain
View Download 0.887 0.004 ubiquitin-dependent protein catabolic process a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.794 0.001 ubiquitin-dependent protein catabolic process a.118.11 Cytochrome c oxidase subunit E
View Download 0.930 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.827 N/A N/A d.224.1 SufE-like

Predicted Domain #2
Region A:
Residues: [186-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSCIDLDKCS HTELVERAVD LSVAAILGDI YNFGELLLHP VFELLVGTQH EWLHDLVIAM  60
   61 NVGDLPLFER LMGQINKM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLLQSSVALL GQKIRLMALI ELVFQLPPNQ RTLTFDTIAR ATRIPSNEVE LLIMRALSVG  60
   61 LITGVIDEVT QIVTISSVQS RILNHSQIAS MESRLREWNQ NIKNLSNVVE ISGKGVFV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.33
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.45730892915196 bayes_pls_golite062009
binding 3.37660003833383 bayes_pls_golite062009
DNA binding 3.14200456972385 bayes_pls_golite062009
nucleic acid binding 3.10521633426493 bayes_pls_golite062009
transcription factor activity 2.53044123488453 bayes_pls_golite062009
hydrolase activity 2.37143167527915 bayes_pls_golite062009
sequence-specific DNA binding 1.81719906294261 bayes_pls_golite062009
transcription activator activity 1.74538136688763 bayes_pls_golite062009
structural constituent of ribosome 1.48815906385664 bayes_pls_golite062009
transcription repressor activity 0.914435149747979 bayes_pls_golite062009
protein binding 0.726445167461826 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.224432853777564 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.142921675412538 bayes_pls_golite062009
small conjugating protein ligase activity 0.124542865343065 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle