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View Structure Prediction Details

Protein: tif35
Organism: Schizosaccharomyces pombe
Length: 282 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tif35.

Description E-value Query
Range
Subject
Range
gi|50938775, gi|... - gi|50938775|ref|XP_478915.1| putative heterogeneous nuclear ribonucleoprotein A1 [Oryza sativa (japo...
176.0 [0..97] [282..1]
gi|114674409 - gi|114674409|ref|XP_001147948.1| PREDICTED: similar to DAZ associated protein 1 isoform 1 [Pan trogl...
174.0 [0..97] [282..30]
gi|40738468, gi|... - gi|67539694|ref|XP_663621.1| hypothetical protein AN6017.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
171.0 [0..1] [280..497]
gi|25470890, gi|... - gi|25470890|ref|NP_733829.1| DAZ associated protein 1 isoform a [Homo sapiens], gi|119589909|gb|EAW6...
170.0 [0..102] [282..10]
gi|70989777, gi|... - gi|70989777|ref|XP_749738.1| heterogeneous nuclear ribonucleoprotein HRP1 [Aspergillus fumigatus Af2...
169.0 [0..11] [281..12]
gi|53127644, gi|... - gi|71894833|ref|NP_001026599.1| DAZ associated protein 1 [Gallus gallus], gi|53127644|emb|CAG31151.1...
169.0 [0..102] [282..11]
gi|89271354 - gi|89271354|emb|CAJ83458.1| DAZ associated protein 1 [Xenopus tropicalis]
168.0 [0..102] [282..10]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKSLDWA DDEDYGTGLP SIQTFDNPDG TKTMIEFRID DNGKKVKVTR VIRKTVITER  60
   61 VQHAVAERKK WKKFGKEAGK NSGVDARTTS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [91-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGENVQLRLQ LGWTTTKEEE QDEAALAAAK VKAKGSSVVR CRACKGNHFT AQCPYKSIIG  60
   61 PVDEPPLDAS PVSSRASGAL GEKGRYIAPH LRAGSGRESG DSMFKRERDD SATLRVTNLS 120
  121 DDTREEELRD LFRRFGGIQR VYLAKDKETG RAKGFAFVSY YDRDCAIKAR DRLDGYGWNN 180
  181 LILRCEFSKP RD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 1ha1A
Description: HNRNP A1 (RBD1,2) FROM HOMO SAPIENS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.50438526063124 bayes_pls_golite062009
nucleic acid binding 3.90076005245206 bayes_pls_golite062009
binding 3.49612884560266 bayes_pls_golite062009
translation initiation factor activity 3.27900316559423 bayes_pls_golite062009
mRNA binding 2.92795844574986 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
1.49431666307335 bayes_pls_golite062009
protein binding 1.32954276279597 bayes_pls_golite062009
single-stranded RNA binding 0.90573796517364 bayes_pls_golite062009
RNA cap binding 0.847034036194541 bayes_pls_golite062009
transcription regulator activity 0.837097200210041 bayes_pls_golite062009
DNA binding 0.828908978889027 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
poly-pyrimidine tract binding 0.32812362201346 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle