YRC Public Data Repository - Protein Structure Prediction

Protein:	fmt1
Organism:	Schizosaccharomyces pombe
Length:	340 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fmt1.

Description	E-value	Query Range	Subject Range
FMT_BACSU - Methionyl-tRNA formyltransferase OS=Bacillus subtilis GN=fmt PE=3 SV=2 FMT_BACSU - Methionyl-tRNA formyltransferase OS=Bacillus subtilis (strain 168) GN=fmt PE=3 SV=2 gi\|221318697 - gi\|221318697\|ref\|ZP_03599991.1\| methionyl-tRNA formyltransferase [Bacillus subtilis subsp. subtilis ... gi\|221313773 - gi\|221313773\|ref\|ZP_03595578.1\| methionyl-tRNA formyltransferase [Bacillus subtilis subsp. subtilis ... gi\|221322968 - gi\|221322968\|ref\|ZP_03604262.1\| methionyl-tRNA formyltransferase [Bacillus subtilis subsp. subtilis ...	317.0	[0..8]	[338..3]
FMT_BACLD - Methionyl-tRNA formyltransferase OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / ...	317.0	[0..8]	[338..3]
gi\|1772500\|emb\|C... - Met-tRNAi formyl transferase [Bacillus subtilis] gi\|1772500 - gi\|1772500\|emb\|CAA71350.1\| Met-tRNAi formyl transferase [Bacillus subtilis]	312.0	[0..8]	[338..3]
FMT_GEOMG - Methionyl-tRNA formyltransferase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)...	311.0	[0..7]	[338..4]
FMT_ECODH - Methionyl-tRNA formyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=fmt PE=3 SV=1 FMT_ECOHS - Methionyl-tRNA formyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=fmt PE=3 SV=1 gi\|85676754, gi\|... - gi\|89110723\|ref\|AP_004503.1\| 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase [E... EG11268 - 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase / Methionyl-tRNA formyltransfer... FMT_ECOLI - Methionyl-tRNA formyltransferase (EC 2.1.2.9) - Escherichia coli EG11268 - 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase / Methionyl-tRNA formyltransfer... gi\|124498111, gi... - gi\|124532221\|ref\|ZP_01702159.1\| methionyl-tRNA formyltransferase [Escherichia coli B], gi\|124498111\|... gi\|194439996, gi... - gi\|83584646\|ref\|ZP_00923313.1\| COG0223: Methionyl-tRNA formyltransferase [Escherichia coli 101-1], g... FMT_ECOLC - Methionyl-tRNA formyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=fmt P... FMT_ECOBW - Methionyl-tRNA formyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=fmt PE=3 SV=1 gi\|242378814, gi... - gi\|251786541\|ref\|YP_003000845.1\| hypothetical protein B21_03089 [Escherichia coli BL21], gi\|24237881... gi\|253979272, gi... - gi\|254289965\|ref\|YP_003055713.1\| methionyl-tRNA formyltransferase [Escherichia coli BL21(DE3)], gi\|2... gi\|254038448, gi... - gi\|254038448\|ref\|ZP_04872504.1\| methionyl-tRNA formyltransferase [Escherichia sp. 1_1_43], gi\|226838... gi\|253975116, gi... - gi\|254163215\|ref\|YP_003046323.1\| methionyl-tRNA formyltransferase [Escherichia coli B str. REL606], ...	310.0	[0..1]	[337..1]
FMT_SHIDS - Methionyl-tRNA formyltransferase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=fmt PE=3 SV=1	310.0	[0..1]	[338..1]
gi\|193066482, gi... - gi\|75255414\|ref\|ZP_00727226.1\| COG0223: Methionyl-tRNA formyltransferase [Escherichia coli E22], gi\|... gi\|194430290, gi... - gi\|75208438\|ref\|ZP_00708767.1\| COG0223: Methionyl-tRNA formyltransferase [Escherichia coli B171], gi... FMT_ECO27 - Methionyl-tRNA formyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=fmt PE=3 SV... FMT_ECO55 - Methionyl-tRNA formyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=fmt PE=3 SV=1 sp\|B7UK11\|FMT_ECO27 - Methionyl-tRNA formyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=fmt PE=3 SV...	310.0	[0..1]	[337..1]
gi\|254795224, gi... - gi\|254795224\|ref\|YP_003080061.1\| 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferas... FMT_ECO57 - Methionyl-tRNA formyltransferase OS=Escherichia coli O157:H7 GN=fmt PE=3 SV=3 gi\|25320684, gi\|... - pir\|\|E85993 hypothetical protein fmt [imported] - Escherichia coli (strain O157:H7, substrain EDL93... gi\|168758515, gi... - gi\|189354684\|gb\|EDU73103.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4401],... gi\|15803815, gi\|... - gi\|15803815\|ref\|NP_289849.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 EDL933], gi\|... gi\|217320751, gi... - gi\|217324530\|ref\|ZP_03440614.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. TW14... FMT_ECO5E - Methionyl-tRNA formyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=fmt PE=3 SV=1 gi\|208818701, gi... - gi\|208818701\|ref\|ZP_03259021.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC40... gi\|208733665, gi... - gi\|208812388\|ref\|ZP_03253717.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC40... gi\|188998872, gi... - gi\|188998872\|gb\|EDU67858.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4076],... gi\|168777855, gi... - gi\|187767010\|gb\|EDU30854.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4196],... gi\|189361852, gi... - gi\|189361852\|gb\|EDU80271.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4486],... gi\|189365130, gi... - gi\|189365130\|gb\|EDU83546.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4501],... gi\|208807557, gi... - gi\|208807557\|ref\|ZP_03249894.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC42... gi\|195939835 - gi\|195939835\|ref\|ZP_03085217.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC40... gi\|15833407, gi\|... - gi\|15833407\|ref\|NP_312180.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. Sakai],... gi\|168802717, gi... - gi\|189375352\|gb\|EDU93768.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC508], ... gi\|189374012, gi... - gi\|189374012\|gb\|EDU92428.1\| methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC869], ...	309.0	[0..1]	[337..1]
FMT_ECOLI - (P23882) Methionyl-tRNA formyltransferase (EC 2.1.2.9)	309.0	[0..4]	[337..1]
FMT_SHISS - Methionyl-tRNA formyltransferase OS=Shigella sonnei (strain Ss046) GN=fmt PE=3 SV=1	309.0	[0..1]	[338..1]

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Predicted Domain #1

Region A:
Residues: [1-340]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKIPLNVI FLGTDEFSIP ILRKLIGCVQ RVRVVSAGGK RQSRRGEIPL PPAAMEANAN  60
   61 GLEYIKLQDG WKNFHMRPDD QLAITASFGR FVPFKILNQL PYGGINIHPS LLPKYRGAGP 120
  121 VYSTILNGDR LAGVTIQTMD SKQFDKGKSL AQAYLKLNGK ETYTLLTKIL SLGAAGMLEH 180
  181 VLLQSLYLPN CQTNTVAPQI HGRITDTGGL QLISKETFPS FQESWAKKIT PEDAHVNFES 240
  241 MNTQQIYNMS RAFNHVWCIL NNKKVFLYDV HPLHSTSAED WIHMKPGEFA LLEKNLLLVK 300
  301 TLDHVMVIKG GIRLSARKIV DPVEWGKTFN SGRGGRFQYV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.154902
Match:	1fmtA
Description:	Methionyl-tRNAfmet formyltransferase, C-terminal domain; Methionyl-tRNAfmet formyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methionyl-tRNA formyltransferase activity	5.51013755462273	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	5.19882604023997	bayes_pls_golite062009
ligase activity	2.41579019065074	bayes_pls_golite062009
methyltransferase activity	2.27572765999587	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	2.20102068445328	bayes_pls_golite062009
catalytic activity	2.16003793103722	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	1.99841214906509	bayes_pls_golite062009
transferase activity	1.01502594768782	bayes_pls_golite062009
DNA N-glycosylase activity	0.809924940479886	bayes_pls_golite062009
binding	0.752059276178195	bayes_pls_golite062009
nucleic acid binding	0.698214709916015	bayes_pls_golite062009
DNA binding	0.421388681127685	bayes_pls_golite062009
phosphoribosylglycinamide formyltransferase activity	0.0567687847434473	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	0.0124799003650303	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: