YRC Public Data Repository - Protein Structure Prediction

Protein:	tol1
Organism:	Schizosaccharomyces pombe
Length:	353 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tol1.

Description	E-value	Query Range	Subject Range
gi\|85086345 - gi\|85086345\|ref\|XP_957684.1\| hypothetical protein NCU04069 [Neurospora crassa OR74A] gi\|32405550, gi\|... - gi\|32405550\|ref\|XP_323388.1\| hypothetical protein [Neurospora crassa], gi\|28918778\|gb\|EAA28448.1\| hy...	262.0	[0..3]	[345..6]
gi\|145015050, gi... - gi\|39944600\|ref\|XP_361837.1\| hypothetical protein MGG_04311 [Magnaporthe grisea 70-15], gb\|EAA50552....	255.0	[0..2]	[345..3]
orf19.105 - HAL22 CGDID:CAL0002967 Assembly 19, Contig19-10035 (39951, 41132) CDS, translated using codon table ... gi\|68483507, gi\|... - gi\|68483507\|ref\|XP_714314.1\| likely 3'(2')5'-bisphosphate nucleotidase [Candida albicans SC5314], gi...	255.0	[0..2]	[343..42]
HAL22_CANAL - 3'(2'),5'-bisphosphate nucleotidase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HAL22 P... HAL22_CANAL - 3'(2'),5'-bisphosphate nucleotidase 2 OS=Candida albicans GN=HAL22 PE=3 SV=2	255.0	[0..2]	[343..7]
gi\|169606736, gi... - gi\|169606736\|ref\|XP_001796788.1\| hypothetical protein SNOG_06415 [Phaeosphaeria nodorum SN15], gi\|11...	255.0	[0..1]	[343..1]
gi\|42553805, gi\|... - gi\|46136033\|ref\|XP_389708.1\| hypothetical protein FG09532.1 [Gibberella zeae PH-1], gi\|42553805\|gb\|E...	252.0	[0..2]	[343..5]
gi\|70991893, gi\|... - gi\|70991893\|ref\|XP_750795.1\| 3'(2'),5'-bisphosphate nucleotidase [Aspergillus fumigatus Af293], gi\|6...	251.0	[0..1]	[344..64]
DPNP_EMENI - 3'(2'),5'-bisphosphate nucleotidase OS=Emericella nidulans GN=AN1769 PE=1 SV=1 DPNP_EMENI - 3'(2'),5'-bisphosphate nucleotidase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46...	248.0	[0..1]	[344..1]

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Predicted Domain #1

Region A:
Residues: [1-353]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDAEKQLA IAAVRRASYL TEKVFNQLIK EKSAAGALTK DDKSPVTIGD FGAQAIVISM  60
   61 LKDAFPNDPI VGEEDSDFLR ENTQTCSRVW ELVQETIQHA TEYKELGQIK SAEEMMSIID 120
  121 QGSYHGGRNG RMWTLDPIDG TKGFLRGAQY AICLALIENG KPVVSAIGCP NLPYDFNQPE 180
  181 TSPKGIIMSA VRNHGCFQYS LHNEKLEPVQ VHMQDVQNTK DSKFCEGVEA GHSMQGTQEE 240
  241 IAKYLGITRG PTKMDSQAKY ASLARGDGDI YLRLPTKMTF EEKIWDHAGG SLLVEEAGGV 300
  301 VSDMFGKPLD FGVGRTLKNN NGVIAAYKGI FEKVIEATAA VTSKDPHFQK VAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	1k9yA
Description:	3';5'-adenosine bisphosphatase, PAP phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.88760626317651	bayes_pls_golite062009
phosphatase activity	2.35747587631464	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.15974571805101	bayes_pls_golite062009
catalytic activity	2.13229228332707	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.56919997723952	bayes_pls_golite062009
3'(2'),5'-bisphosphate nucleotidase activity	1.47057191917686	bayes_pls_golite062009
carbohydrate phosphatase activity	1.42298284519844	bayes_pls_golite062009
fructose 1,6-bisphosphate 1-phosphatase activity	1.27303304175364	bayes_pls_golite062009
binding	0.836667162379626	bayes_pls_golite062009
nucleotidase activity	0.335234714648046	bayes_pls_golite062009
protein binding	0.0338617836572318	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: