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View Structure Prediction Details

Protein: cbh1
Organism: Schizosaccharomyces pombe
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cbh1.

Description E-value Query
Range
Subject
Range
gi|2501794 - gi|2501794|gb|AAB80698.1| Cbhp [Schizosaccharomyces pombe]
453.0 [0..1] [514..1]
gi|34860486, gi|... - gi|34860486|ref|XP_235818.2| PREDICTED: similar to jerky homolog-like [Rattus norvegicus], gi|157822...
406.0 [0..3] [510..5]
JERKL_MOUSE - Jerky protein homolog-like OS=Mus musculus GN=Jrkl PE=2 SV=1
405.0 [0..3] [510..5]
gi|145015325, gi... - gi|39966430|ref|XP_365196.1| hypothetical protein MGG_10041 [Magnaporthe grisea 70-15], gb|EAA49877....
395.0 [0..6] [488..2]
cbh2 - centromere binding protein Cbh2
CBH2_SCHPO - CENP-B homolog protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cbh2 PE=3 SV=1
393.0 [0..1] [513..1]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPIRQAVSL AEKKAIRDYY NQSAHRIPQK EVTEWFRKTY NKDLSQSTIS EILSPKYSYL  60
   61 DDGSVRLGDI KKIRAPKFPL LDNAVYEWLQ QREVEGLPIS GDMIKQAATR FWSKIPAYAS 120
  121 LPLPDFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1iufA
Description: Ars-binding protein 1, ABP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
transcription repressor activity 3.55154985983449 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription corepressor activity 1.49423102874486 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
cytoskeletal protein binding 1.24134446233807 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
centromeric DNA binding 1.13545283098583 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.922310816608639 bayes_pls_golite062009
histone acetyltransferase activity 0.922310816608639 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
DNA-dependent ATPase activity 0.666799964992178 bayes_pls_golite062009
actin binding 0.6102552688489 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
telomeric DNA binding 0.284650049512347 bayes_pls_golite062009
DNA helicase activity 0.187022204923867 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.141400887946529 bayes_pls_golite062009
protein deacetylase activity 0.13314897698019 bayes_pls_golite062009
structure-specific DNA binding 0.105174598157041 bayes_pls_golite062009
histone deacetylase activity 0.0878521297613482 bayes_pls_golite062009
nucleotidyltransferase activity 0.00788099347317628 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [128-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGWLDKFRRR HYIQQSAVNQ ALESIKFEVF REYPVHIQEF IRPYAQKDIF CVGGTSLFWK  60
   61 LTPNKQNLDY QEIQGMKRGK AKVSLIMCCN ADGSERLPLW IVGYAQNPRS FEQCGIFPKS 120
  121 MNFEWKWNGR ASISPIIMEE WLRWFDTRMQ GRKVLLMLES NDTYQFGVES VRRFKGGFQN 180
  181 TSVFRIPEKT LDIKSPFEQG IVDTFKANYR RYWLQYSLNQ INILRDPLKA VNVLKAIRWM 240
  241 LWSWNFGVSE KTIQASFLRS GLLGPHSEAE GQGM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.43
Match: 2f7tA
Description: No description for 2f7tA was found.

Predicted Domain #3
Region A:
Residues: [402-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESYQKAIMEI GNLISSKGSE AVKQINEYIR PSEEDETKLH QDAVDTVAAE FLEERRFESD  60
   61 EEEDVEPQIS NVEAAMAFEV LIKYFEQHEN GDPSFVLDLY RRQRVIAPNN LIA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle