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View Structure Prediction Details

Protein: CG1753-PA, CG175...
Organism: Drosophila melanogaster
Length: 522 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1753-PA, CG175....

Description E-value Query
Range
Subject
Range
gi|114684524 - gi|114684524|ref|XP_001142443.1| PREDICTED: cystathionine-beta-synthase isoform 3 [Pan troglodytes]
381.0 [0..2] [521..33]

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Predicted Domain #1
Region A:
Residues: [1-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQPKPYERP ADFIDPGKPS KCKWHLGTAE KSPHIHRGIA HRQQITPNIL EVIGCTPLVK  60
   61 LNNIPASDGI ECEMYAKCEF LNPGGSVKDR IGYRMVQDAE EQGLLKPGYT IIEPTSGNTG 120
  121 IGLAMACAVK GYKCIIVMPE KMSNEKVSAL RTLGAKIIRT PTEAAYDSPE GLIYVAQQLQ 180
  181 RETPNSIVLD QYRNAGNPLA HYDGTAAEIL WQLDNKVDMI VVSAGTAGTI SGIGRKIKEQ 240
  241 VPSCQIVGVD PYGSILARPA ELNKTDVQFY EVEGIGYDFP PTVFDDTVVD VWTKIGDSDC 300
  301 FPMSRRLNAE EGLLCGGSSG GAMHAALEHA RKLKKGQRCV VILPDGIRNY MTKFVSDNWM 360
  361 EARNFKEPVN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1jbqA
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.18562032111987 bayes_pls_golite062009
cystathionine beta-synthase activity 2.46824200933572 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
tryptophan synthase activity 1.04832999357666 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
binding 0.791501201936306 bayes_pls_golite062009
threonine synthase activity 0.727838845253199 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.37325071016009 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [371-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHGHWWWSLA IAELELPAPP VILKSDATVG EAIALMKKHR VDQLPVVDQD DGSVLGVVGQ  60
   61 ETLITQIVSM NRQQSDPAIK ALNKRVIRLN ESEILGKLAR VLEVDPSVLI LGKNPAGKVE 120
  121 LKALATKLDV TTFIAAGKQK PKANGTTNGG SH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 2v8qE
Description: No description for 2v8qE was found.

Predicted functions:

Term Confidence Notes
binding 1.03812086384118 bayes_pls_golite062009
oxidoreductase activity 0.683927541769979 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.333489822810031 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.240245563840066 bayes_pls_golite062009
catalytic activity 0.181756622780318 bayes_pls_golite062009
protein binding 0.069261088689358 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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