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View Structure Prediction Details

Protein: FBpp0311837, run-PA
Organism: Drosophila melanogaster
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311837, run-PA.

Description E-value Query
Range
Subject
Range
gi|46228363 - gi|46228363|gb|EAK89262.1| putative DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' ...
gi|66359288 - gi|66359288|ref|XP_626822.1| DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' subunit...
237.0 [0..115] [509..1460]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLPAGPTMV ANNTQVLAAA AAAAAAAAAA VAQGPGPQQS SNATTASAIA INPAQSLANT  60
   61 STHSASSTGS STPDLSTNNT SSSSNATTSP QNSAKMPSSM TDMFASLHEM LQEY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGELAQTGSP SILCSALPNH WRSNKSLPGA FKVIALDDVP DGTLVSIKCG NDENYCGELR  60
   61 NCTTTMKNQV AKFNDLRFVG RSGRGKSFTL TITIATYPVQ IASYSKAIKV TVDGPREPRS 120
  121 KQSYGYPHPG AFNPFMLNPA WLDAAYMTYG YAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1e50A
Description: Acute myeloid leukemia 1 protein (AML1), RUNT domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13591399970354 bayes_pls_golite062009
nucleic acid binding 0.54158309583174 bayes_pls_golite062009
DNA binding 0.53363287856737 bayes_pls_golite062009
transcription regulator activity 0.3602964037518 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [268-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFRHQAAAQA AQVHHPALAK SSASSVSPNP NPSVATSSSS AVQPSEYPHP AAAVAAAAGQ  60
   61 PAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [331-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMPSPPGAAP ATPYAIPQFP FNHVAAAAAA KAATPHAFHP YNFAAAAGLR ARNAALHHQS  60
   61 EPVHVSPASS RPSSSSPTQQ HVLLKLNTSI ETSSIHEQSA SDGDSDDEQI DVVKSEFDLD 120
  121 KSLDVAPLRM RCDLKAPSAM KPLYHESGPG AVANSRQPSP ETTTKIKSAA VQQKTVWRPY 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle