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View Structure Prediction Details

Protein: FBpp0311837, run-PA
Organism: Drosophila melanogaster
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311837, run-PA.

Description E-value Query
Range
Subject
Range
gi|46228363 - gi|46228363|gb|EAK89262.1| putative DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' ...
gi|66359288 - gi|66359288|ref|XP_626822.1| DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' subunit...
237.0 [0..115] [509..1460]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLPAGPTMV ANNTQVLAAA AAAAAAAAAA VAQGPGPQQS SNATTASAIA INPAQSLANT  60
   61 STHSASSTGS STPDLSTNNT SSSSNATTSP QNSAKMPSSM TDMFASLHEM LQEY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGELAQTGSP SILCSALPNH WRSNKSLPGA FKVIALDDVP DGTLVSIKCG NDENYCGELR  60
   61 NCTTTMKNQV AKFNDLRFVG RSGRGKSFTL TITIATYPVQ IASYSKAIKV TVDGPREPRS 120
  121 KQSYGYPHPG AFNPFMLNPA WLDAAYMTYG YAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1e50A
Description: Acute myeloid leukemia 1 protein (AML1), RUNT domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13591399970354 bayes_pls_golite062009
nucleic acid binding 0.54158309583174 bayes_pls_golite062009
DNA binding 0.53363287856737 bayes_pls_golite062009
transcription regulator activity 0.3602964037518 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [268-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFRHQAAAQA AQVHHPALAK SSASSVSPNP NPSVATSSSS AVQPSEYPHP AAAVAAAAGQ  60
   61 PAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [331-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMPSPPGAAP ATPYAIPQFP FNHVAAAAAA KAATPHAFHP YNFAAAAGLR ARNAALHHQS  60
   61 EPVHVSPASS RPSSSSPTQQ HVLLKLNTSI ETSSIHEQSA SDGDSDDEQI DVVKSEFDLD 120
  121 KSLDVAPLRM RCDLKAPSAM KPLYHESGPG AVANSRQPSP ETTTKIKSAA VQQKTVWRPY 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle