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View Structure Prediction Details

Protein: CG9581-PA
Organism: Drosophila melanogaster
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9581-PA.

Description E-value Query
Range
Subject
Range
gi|54643255, gi|... - gi|54643255|gb|EAL31999.1| GA21891-PA [Drosophila pseudoobscura], gi|125981879|ref|XP_001354943.1| G...
427.0 [0..1] [544..1]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILRRLDRL IAPTVRRSAA ISTSLWPHRW MSQSTTISPG SPSSKSTVNA AEVRGVAQIL  60
   61 RQQKGNLGQP TSVSHPHLIQ PDEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPGVELTEIK ERRSQLMQNI RAYARSFGGE FNGHSSSCHM LVLGAASKKY MSGKIPYVFR  60
   61 QNSDFYYLTG CLEPDAVLLL TIDEAQNVQS ELFMRPKDPH AELWDGPRTG PELAVPLFGV 120
  121 TEAHPLSQLE AVLAKRAGAL KPHIWFDQKS TDLPSLAENM LRLSGNQQRP LLPAYTFLEA 180
  181 MRLLKSRDEM QLMRRTCDIA SRSFNEVMAE TRPGQSEHHL FAAIDYKCRM RNASYLAYPP 240
  241 VVAAGKNATV IHYVANSQLL GQQDLVLMDA GCEYGGYTSD ITRTWPASGV FTEPQRTLYD 300
  301 MLHQLQEEII GNVMKPGGET LDQLFETTCY KLGKYLQEIG LVGKSFSEYK ELVSQGYRFC 360
  361 PHHVSHYLGM DVHDTPHVPR NTRIVPGMVF TVEPGIYIGQ DCGDVPPEFR GIGIRIEDDL 420
  421 LINENGHVEV LTEACVKDPR ALQELCKQQQ KNPGASSAEA F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.0
Match: 1a16A
Description: AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.60615909541559 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.18503136472662 bayes_pls_golite062009
metallopeptidase activity 1.75829852010848 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
binding 0.863418237728554 bayes_pls_golite062009
exopeptidase activity 0.762255574851485 bayes_pls_golite062009
nucleic acid binding 0.478507702690501 bayes_pls_golite062009
protein binding 0.154618857315218 bayes_pls_golite062009
transcription regulator activity 0.151893946259744 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009
DNA binding 0.146627179138465 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle