| Protein: | eag-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1174 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for eag-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
670.0 | [0..1] | [1116..1] |
|
Region A: Residues: [1-76] |
1 11 21 31 41 51
| | | | | |
1 MPGGRRGLVA PQNTFLENII RRSNSQPDSS FLLANAQIVD FPIVYCNESF CKISGYNRAE 60
61 VMQKSCRYVC GFMYGE
|
| Detection Method: |  |
| Confidence: | 19.522879 |
| Match: | 1bywA |
| Description: | Erg potassium channel, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [77-430] |
1 11 21 31 41 51
| | | | | |
1 LTDKETVGRL EYTLENQQQD QFEILLYKKN NLQCGCALSQ FGKAQTQETP LWLLLQVAPI 60
61 RNERDLVVLF LLTFRDITAL KQPIDSEDTK GVLGLSKFAK LARSVTRSRQ FSAHLPTLKD 120
121 PTKQSNLAHM MSLSADIMPQ YRQEAPKTPP HILLHYCAFK AIWDWVILCL TFYTAIMVPY 180
181 NVAFKNKTSE DVSLLVVDSI VDVIFFIDIV LNFHTTFVGP GGEVVSDPKV IRMNYLKSWF 240
241 IIDLLSCLPY DVFNAFDRDE DGIGSLFSAL KVVRLLRLGR VVRKLDRYLE YGAAMLILLL 300
301 CFYMLVAHWL ACIWYSIGRS DADNGIQYSW LWKLANVTQS PYSYIWSNDT GPEL
|
| Detection Method: | |
| Confidence: | 4.09691 |
| Match: | 2nyyA |
| Description: | No description for 2nyyA was found. |
| Term | Confidence | Notes |
| substrate-specific transmembrane transporter activity | 2.4673993239115 | bayes_pls_golite062009 |
| binding | 1.56259855231916 | bayes_pls_golite062009 |
| transporter activity | 1.29150662073327 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07075219961504 | bayes_pls_golite062009 |
| amine binding | 0.947632395806172 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.801327928563072 | bayes_pls_golite062009 |
| signal transducer activity | 0.705049527437737 | bayes_pls_golite062009 |
| molecular transducer activity | 0.705049527437737 | bayes_pls_golite062009 |
| protein binding | 0.657665757061848 | bayes_pls_golite062009 |
| 0.394278984078131 | bayes_pls_golite062009 | |
| channel regulator activity | 0.37785202181286 | bayes_pls_golite062009 |
| receptor activity | 0.286006388683751 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.0601638402237312 | bayes_pls_golite062009 |
|
Region A: Residues: [431-516] |
1 11 21 31 41 51
| | | | | |
1 VNGPSRKSMY VTALYFTMTC MTSVGFGNVA AETDNEKVFT ICMMIIAALL YATIFGHVTT 60
61 IIQQMTSATA KYHDMLNNVR EFMKLH
|
| Detection Method: | |
| Confidence: | 3.7 |
| Match: | 2qksA |
| Description: | No description for 2qksA was found. |
|
Region A: Residues: [517-705] |
1 11 21 31 41 51
| | | | | |
1 EVPKALSERV MDYVVSTWAM TKGLDTEKVL NYCPKDMKAD ICVHLNRKVF NEHPAFRLAS 60
61 DGCLRALAMH FMMSHSAPGD LLYHTGESID SLCFIVTGSL EVIQDDEVVA ILGKGDVFGD 120
121 QFWKDSAVGQ SAANVRALTY CDLHAIKRDK LLEVLDFYSA FANSFARNLV LTYNLRHRLI 180
181 FRKVADVKR
|
| Detection Method: | |
| Confidence: | 42.69897 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| metal ion transmembrane transporter activity | 10.0964834385956 | bayes_pls_golite062009 |
| cation channel activity | 9.88287212109635 | bayes_pls_golite062009 |
| ion channel activity | 9.4846197809463 | bayes_pls_golite062009 |
| channel activity | 9.25176207085973 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 9.25176207085973 | bayes_pls_golite062009 |
| substrate-specific channel activity | 9.2472549851376 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| gated channel activity | 9.19042473454294 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 8.67936023319976 | bayes_pls_golite062009 |
| voltage-gated channel activity | 8.65591260847522 | bayes_pls_golite062009 |
| potassium channel activity | 8.63993986153386 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 7.73925918789438 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 7.4836902710921 | bayes_pls_golite062009 |
| cyclic nucleotide-gated ion channel activity | 7.4836902710921 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 7.28268657394688 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 6.98507387897677 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 5.54400173845933 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 5.34760703274696 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 5.1138025954757 | bayes_pls_golite062009 |
| transporter activity | 3.30740141256752 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.24402760485462 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.22443361822344 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 1.73579819368652 | bayes_pls_golite062009 |
| binding | 1.39247933044015 | bayes_pls_golite062009 |
| signal transducer activity | 0.758143612871078 | bayes_pls_golite062009 |
| molecular transducer activity | 0.758143612871078 | bayes_pls_golite062009 |
| protein binding | 0.71319432010926 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.263984709287237 | bayes_pls_golite062009 |
|
Region A: Residues: [706-854] |
1 11 21 31 41 51
| | | | | |
1 EKELAERRKN EPQLPQNQDH LVRKIFSKFR RTPQVQAGSK ELVGGSGQSD VEKGDGEVER 60
61 TKVFPKAPKL QASQATLARQ DTIDEGGEVD SSPPSRDSRV VIEGAAVSSA TVGPSPPVAT 120
121 TSSAAAGAGV SGGPGSGGTV VAIVTKADR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [855-1174] |
1 11 21 31 41 51
| | | | | |
1 NLALERERQI EMASSRATTS DTYDTGLRET PPTLAQRDLI ATVLDMKVDV RLELQRMQQR 60
61 IGRIEDLLGE LVKRLAPGAG SGGNAPDNSS GQTTPGDEIC AGCGAGGGGT PTTQAPPTSA 120
121 VTSPVDTVIT ISSPGASGSG SGTGAGAGSA VAGAGGAGLL NPGATVVSSA GGNGLGPLML 180
181 KKRRSKSRKA PAPPKQTLAS TAGTATAAPA GVAGSGMTSS APASADQQQQ HQSTADQSPT 240
241 TPGAELLHLR LLEEDFTAAQ LPSTSSGGAG GGGGSGSGAT PTTPPPTTAG GSGSGTPTST 300
301 TATTTPTGSG TATRGKLDFL
|
| Detection Method: | |
| Confidence: | 41.69897 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
