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View Structure Prediction Details

Protein: FBpp0304587
Organism: Drosophila melanogaster
Length: 528 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304587.

Description E-value Query
Range
Subject
Range
gi|109109354 - gi|109109354|ref|XP_001112126.1| PREDICTED: similar to suppression of tumorigenicity 14 [Macaca mula...
347.0 [0..14] [525..575]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLHLAAILI LCIEHVTKAV AQGMPISPCP KVFQYRFDGS EWFGLMAVRS PDGHQPLHIR  60
   61 VTLSMRGKPT TNYLGEIELL TRGKFTHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.39794
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.17967257091654 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.2470239332285 bayes_pls_golite062009
endopeptidase activity 2.22068546360893 bayes_pls_golite062009
receptor activity 1.99032940347865 bayes_pls_golite062009
binding 1.78499809874825 bayes_pls_golite062009
signal transducer activity 1.50733812954653 bayes_pls_golite062009
molecular transducer activity 1.50733812954653 bayes_pls_golite062009
metalloendopeptidase activity 1.39151268274571 bayes_pls_golite062009
metallopeptidase activity 1.34388258592372 bayes_pls_golite062009
hydrolase activity 0.896082165571875 bayes_pls_golite062009
transcription regulator activity 0.884990148156594 bayes_pls_golite062009
protein binding 0.452894757163315 bayes_pls_golite062009
catalytic activity 0.075748351866431 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [89-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVLYKIRFP KHHFPPKLLL MSANNHVICF GSGEHSIFMT QIQLEHIRKL SFIPDKKSSL  60
   61 LLDPEEEEVR KTDDKPPSTP HIQFKKKPFA QAPKEICGRI DRDLDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [195-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLSQRTESLH VAIGEPKSSD GITSPVFVDD DEDDVLEHQF VDESEAEAIE SDSADSLPSI  60
   61 TRGSWPWLAA IYVNNLTSLD FQCGGSLVSA RVVISSAHCF KLFNKRYTSN EVLVFLGRHN 120
  121 LKNWNEEGSL AAPVDGIYIH PDFNSQLSSY DADIAVIILK DEVRFNTFIR PACLWSGSSK 180
  181 TEYIVGERGI VIGWSFDRTN RTRDQKLSSE LPGKKSTDAS APKVVKAPIV GNAECFRANA 240
  241 HFRSLSSNRT FCAGIQAEER DTHQSGASIY TGISGAGLFI RRNNRWMLRG TVSAALPAVE 300
  301 TPDAESSHKL CCKNQYIIYA DVAKFLDWIT AFVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.09691
Match: 1mkwK
Description: Thrombin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.91209560688646 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.52773635813967 bayes_pls_golite062009
serine hydrolase activity 5.5105092190926 bayes_pls_golite062009
serine-type peptidase activity 5.49703869306079 bayes_pls_golite062009
serine-type endopeptidase activity 5.39623690248556 bayes_pls_golite062009
endopeptidase activity 5.32070018460528 bayes_pls_golite062009
fucose binding 3.5000591397073 bayes_pls_golite062009
hydrolase activity 3.09595791887493 bayes_pls_golite062009
calcium-dependent protein binding 1.96509840108953 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009
binding 1.30738106455622 bayes_pls_golite062009
receptor activity 1.10676631226741 bayes_pls_golite062009
receptor binding 1.06765011459469 bayes_pls_golite062009
nucleic acid binding 1.03130756227487 bayes_pls_golite062009
molecular transducer activity 0.885246794092463 bayes_pls_golite062009
signal transducer activity 0.885246794092463 bayes_pls_golite062009
calcium ion binding 0.753095272942721 bayes_pls_golite062009
DNA binding 0.559109234340392 bayes_pls_golite062009
monosaccharide binding 0.414984014288226 bayes_pls_golite062009
glycosaminoglycan binding 0.33404934673697 bayes_pls_golite062009
protein binding 0.253694583401977 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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