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View Structure Prediction Details

Protein: gi|22833104, gi|...
Organism: Drosophila melanogaster
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22833104, gi|....

Description E-value Query
Range
Subject
Range
gi|531471, gi|21... - gi|531471|gb|AAA64560.1| phosphorylase kinase gamma, pir||S51600 phosphorylase kinase (EC 2.7.1.38) ...
344.0 [0..1] [473..1]

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Predicted Domain #1
Region A:
Residues: [1-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKDEEDDLL PDKDAAKGFY AKYEPKEILG RGISSTVRRC IEKETGKEFA AKIIDLGATT  60
   61 ESGETNPYHM LEATRQEISI LRQVMGHPYI IDLQDVFESD AFVFLVFELC PKGELFDYLT 120
  121 SVVTLSEKKT RTIMRQIFEG VEYIHAKSIV HRDLKPENIL LDENHNVKIT DFGFAKQLQE 180
  181 GEKLTNLCGT PGYLAPETLK CNMFEGSPGY SQEVDIWACG VIMFTLLVGC PPFWHRKQMV 240
  241 MLRNIMEGKY SFTSPEWADI SEDPKDLIRK CLVVDPSQRI TVKEVLRHPF FNQMVLMGDR 300
  301 RHPAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.0
Match: 1ql6A
Description: gamma-subunit of glycogen phosphorylase kinase (Phk)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 4.31938467136214 bayes_pls_golite062009
phosphorylase kinase activity 4.23570595363447 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
protein binding 2.276111749106 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
insulin receptor substrate binding 1.62657794525303 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
MAP kinase activity 0.81943579965027 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
actin binding 0.368012533063159 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
protein complex binding 0.343240719858581 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.22068623224846 bayes_pls_golite062009
cytoskeletal protein binding 0.214293154365587 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [306-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIAPAQTNSR HLLQPEASSY RFGQLNSSCA GAPNYLYCAP QSSYSSNRMR DGALDDAGAS  60
   61 AASATCHVMS PSNASNSYAT NTTANTSNSA LASASSHKTL TAMVYYQQQP QQHQTQQQQQ 120
  121 QYQQQQTTQL PVQLQLQHPL LQTGGDGKQS VYAPPTVQAA AQTKSLQRAQ KVPIRHTRDT 180
  181 GHHSDTAPTL HRRAAAR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle