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View Structure Prediction Details

Protein: ras-PC, FBpp0304...
Organism: Drosophila melanogaster
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ras-PC, FBpp0304....

Description E-value Query
Range
Subject
Range
gi|166853413, gi... - gi|167039173|ref|YP_001662158.1| response regulator receiver protein [Thermoanaerobacter sp. X514], ...
gi|167038115, gi... - gi|76796702|ref|ZP_00779057.1| IMP dehydrogenase [Thermoanaerobacter ethanolicus ATCC 33223], gi|765...
gi|241902681, gi... - gi|241902681|ref|ZP_04787413.1| inosine-5'-monophosphate dehydrogenase [Thermoanaerobacter brockii s...
423.0 [0..44] [534..2]

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Predicted Domain #1
Region A:
Residues: [1-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESTTKVKVN GFVESTSSSA APAIQTKSTT GFDAELQDGL SCKELFQNGE GLTYNDFLIL  60
   61 PGYIDFTAEE VDLSSPLTKS LTLRAPLVSS PMDTVTESEM AIAMALCGGI GIIHHNCTPE 120
  121 YQALEVHKVK KYKHGFMRDP SVMSPTNTVG DVLEARRKNG FTGYPVTENG KLGGKLLGMV 180
  181 TSRDIDFREN QPEVLLADIM TTELVTAPNG INLPTANAIL EKSKKGKLPI VNQAGELVAM 240
  241 IARTDLKKAR SYPNASKDSN KQLLVGAAIG TRSEDKARLA LLVANGVDVI ILDSSQGNSV 300
  301 YQVEMIKYIK ETYPELQVIG GNVVTRAQAK NLIDAGVDGL RVGMGSGSIC ITQEVMACGC 360
  361 PQATAVYQVS TYARQFGVPV IADGGIQSIG HIVKAIALGA SAVMMGSLLA GTSEAPGEYF 420
  421 FSDGVRLKKY RGMGSLEAME RGDAKGAAMS RYYHNEMDKM KVAQGVSGSI VDKGSVLRYL 480
  481 PYLECGLQHS CQDIGANSIN KLRDMIYNGQ LRFMKRTHSA QLEGNVHGLF SYEKRLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.0
Match: 1b3oA
Description: Inosine monophosphate dehydrogenase (IMPDH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
IMP dehydrogenase activity 2.02048863053452 bayes_pls_golite062009
binding 0.964202692685807 bayes_pls_golite062009
transporter activity 0.961062314616209 bayes_pls_golite062009
transmembrane transporter activity 0.807029018941177 bayes_pls_golite062009
substrate-specific transporter activity 0.640881170978843 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.525366315833255 bayes_pls_golite062009
ion transmembrane transporter activity 0.440262824681055 bayes_pls_golite062009
protein binding 0.22179604283012 bayes_pls_golite062009
catalytic activity 0.181756622780318 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.0973526732376297 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle