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View Structure Prediction Details

Protein: Edem1-PA, FBpp02...
Organism: Drosophila melanogaster
Length: 982 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Edem1-PA, FBpp02....

Description E-value Query
Range
Subject
Range
gi|2832777 - gi|2832777|emb|CAA15933.1| EG:86E4.2 [Drosophila melanogaster]
1379.0 [0..1] [963..1]

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Predicted Domain #1
Region A:
Residues: [1-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQKPRNNGY PGTLICAVLL VLLSTGVSGQ KQYSKARKLE LREDVRRMFQ HAYDGYLRHA  60
   61 SNYDELRPLT CDGHDTWGSY SLTLIDALDT LATMGNFTEF RRAARLLEEK MDFDRDINVS 120
  121 VFETNIRIVG GLLSAHLLSK RAGVELEPGW PCKGPLLRLA EDVARRLLPA FVTNTGMPYG 180
  181 TVNLRYGVPK GETSITCTAG VGTFLIEFGT LSRLTGKTIY EDVAMKAVHA LWAYRSPIGL 240
  241 FGNHIDVQSG RWTALDSGIG AGVDSLFEYL VKASVLLNRP ELLELFHEAR AAIDKYMRKE 300
  301 DWYVWVGMNK GRVTLPVFQS LEAFWPGILS IIGDTEPALR TISRYIGVWK KYGFLPEFYN 360
  361 IAAGEASPNR EVYPLRPELI ESAMYLYRAT GNEYLLEFGE HMLETLEFSA KTKCGYATIR 420
  421 NVVTHEKENR MESFFLAETS KYLYLLFDEE NFLHNDGSGG ELLSTEDDVC VVQAGAYIFN 480
  481 TEAHPMDMSA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 160.0
Match: 1nxcA
Description: Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 4.49187091491308 bayes_pls_golite062009
mannosyl-oligosaccharide mannosidase activity 4.31101035324444 bayes_pls_golite062009
mannosidase activity 4.13262307600704 bayes_pls_golite062009
hydrolase activity 2.37587225454998 bayes_pls_golite062009
catalytic activity 1.68917300409014 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 1.48699707323226 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 1.32469433621478 bayes_pls_golite062009
binding 0.581699672540981 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [491-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHCCHAHNED IYTSLDLQRF SPRAILERSK KRQVAVQEQW VPQCHPENNE FFNKEDESVQ  60
   61 AQDSEKEQER EQSGTSTTMA VDIEVFDEFQ QPAGDLLVSN FEQIREEREL NESLHRNVVA 120
  121 RNQLTVSDLD EFFAQRRESF ASASEALNYV KTFMG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [646-898]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYTMDVAFIR GLQLYDTNMS SVLGTGAQKE YESRMRTLWQ LYELQQQYVA NIRVIQGLGL  60
   61 LTFPADGDRI PSHLTEVLDS LDKSAHLEHM DLQDLETRVS NTSSPQLAHI REVILKARNA 120
  121 YAIAMVNTSA MQEFAIRIYL SGTSEAGVRI HPLLEDGELS EEARKRPLKL AEERALFSYA 180
  181 RRIVDFRKRM AETVDRLQTL MQDIPPPKRK EATTDSQAAD ASTVYTQTKA QMAAPAQQPE 240
  241 PSQEEKQSTQ IQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [899-982]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKLAENGSGL GEEESGCVWS QLVQTILRKT TVQRVKFDEA VLQENTRKAL EKYARKELPH  60
   61 HLFACHRPEY IEGFAYRDFY PEAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle