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View Structure Prediction Details

Protein: FBpp0305122, FBp...
Organism: Drosophila melanogaster
Length: 742 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305122, FBp....

Description E-value Query
Range
Subject
Range
CG42666-PF, CG42... - This gene is referred to in FlyBase by the symbol Dmel\CG42666 (CG42666, FBgn0261548).The gene has a...
475.0 [0..1] [742..20]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSCNKNSSS RITTTNNNVT TTSNISGNSS NKRCPQKYTG NTLAVNSNML AYQQQATAGG  60
   61 KNSTRKSRHN NNKQNHQQQQ QQQQQQFDHI HKRNGTAGGT GSECSPAAPT SNWLQRGYGR 120
  121 QFVHSSCIED KLLGHHNPG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRNSTSSDAT SEDIDSSSEL PNKSKGNSCA GSIHASGGSK SRSKRHQKQS GQQTRNPDHN  60
   61 GQRTGAATPC TGQKAKQGNA KWRQQQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [226-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPSSNNQQQ QMQQQMQQQK RGRNKKPGKW SNNIIDNPNS NHGGSSQQKT CDSSSSSALS  60
   61 SPTSSATTSA TSSPTNSPTS YPRANGNRKR IEAALEWRRE QELGRQNANF LVPPLRQYEQ 120
  121 LEFDDKTVVQ Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [357-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRRHIIDNHL LRVYGFPVDS VVHEGAIEIF KCMPHMSFAA ALAETAQAVT VINYHDGLTN  60
   61 RAEEEVANST DSGNSSPQSL DSESGGEWSG SECESSNSSS SSAGEAALGL ELKYCHFVPV 120
  121 ERSLSKPCA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [486-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RCKRHFLVDE LTGQYLTHEE CQYHSGKYQR YYDGVSHGRW TCCNEGEESS PGCCLGDRHV  60
   61 WSGSVVGVNG PYYDFVRTEH RGSGEDE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [573-742]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAVYALDCEM SYTGRGLDVT KVSLVALNGQ LVYEHFVRPV CDIIDYNTQY SGITETDLCS  60
   61 GAKSLAEVQR DLLQLITADT ILIGHGLEND LRALRLVHNT LIDTSISFPH CNGFPYRRAL 120
  121 RHLTKVHLKR DIQAGDGTTG HSSFEDSRAC MELMLWRVNR ELDPAWSWDD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1wljA
Description: human ISG20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 5.30591758406946 bayes_pls_golite062009
exoribonuclease activity 3.71639182685131 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 3.59362615133405 bayes_pls_golite062009
3'-5'-exoribonuclease activity 3.1992647486402 bayes_pls_golite062009
exonuclease activity 3.13676176369406 bayes_pls_golite062009
nuclease activity 3.11657409772275 bayes_pls_golite062009
ribonuclease H activity 2.91966688044755 bayes_pls_golite062009
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 2.75003136922541 bayes_pls_golite062009
endonuclease activity 2.63074055051349 bayes_pls_golite062009
endoribonuclease activity 2.59247838057313 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.57498413015114 bayes_pls_golite062009
hydrolase activity 2.41899414621161 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.04408785855894 bayes_pls_golite062009
3'-5' exonuclease activity 1.44123900197846 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
nucleic acid binding 1.23371034593624 bayes_pls_golite062009
protein binding 1.16870279238939 bayes_pls_golite062009
deoxyribonuclease activity 1.1219517187744 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
DNA binding 0.860359347662869 bayes_pls_golite062009
binding 0.762139256580538 bayes_pls_golite062009
DNA polymerase activity 0.717600245625866 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.708753843279937 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.598360955770972 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.568273228950698 bayes_pls_golite062009
0.49473250705373 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009
exodeoxyribonuclease activity 0.278838342302102 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.261428436029202 bayes_pls_golite062009
structure-specific DNA binding 0.0701825322473915 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.00214157813118243 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle