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View Structure Prediction Details

Protein: br-PI, br-PH, br...
Organism: Drosophila melanogaster
Length: 880 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for br-PI, br-PH, br....

Description E-value Query
Range
Subject
Range
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
578.0 [0..111] [878..461]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTQHFCLR WNNYQSSITS AFENLRDDEA FVDVTLACEG RSIKAHRVVL SACSPYFREL  60
   61 LKSTPCKHPV ILLQDVNFMD LHALVEFIYH GEVNVHQKSL QSFLKTAEVL RVSGLTQQQA 120
  121 EDTHSHLAQI QNLANSGGRT PLNTHTQSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #2
Region A:
Residues: [150-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHPHHGSLHD DGGSSTLFSR QGAGSPPPTA VPSLPSHINN QLLKRMAMMH RSSAAAAAEE  60
   61 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHAFKRLRGS DNSLPLSGAV GSGSNNNSPD LPPLHARSAS PQQTPADFST IKHHNNNNTP  60
   61 PLKEEKRNGP TGNGNSGNGN GNGNGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [297-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGNGISISD KLGSLTPSPL ARAGADDVKS EPMDMVCSNN NANANDEHSN DSTGEHDANR  60
   61 SSSGDGGKGS LSSGNDEEIG DGLASHHAAP QFIMSPAENK MFHAAAFNFP NIDPSALLGL 120
  121 NTQLQQSGDL AVSPQGGSTG SLLSGVIVPG GSGGTPSNSS SNNNNNNSNN QQQKVEQQSS 180
  181 PHQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [480-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLQQQHHSTP HTNSPQLKQE QPKSGGGSCK SSDLHIAAGS ERSLSRSSQG MPDAGGHSAT  60
   61 PSPTAAYHKR ERERERERER ERERERERSL DHERDLERPG GTGSPPPPPP SHHSHFGQHP 120
  121 LSLLPSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [607-696]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQLHATHHEL SAAAAHHAHA HAHAAHAHAL ARAGSPMEHH HLLHHRRASL SPSGAVSSAS  60
   61 GAGGRGGGAG GPGGPGGSLL SSVRAQDVAQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [697-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANRLLLPLPL NACHRCDVCG KLLSTKLTLK RHKEQQHLQP LNNAVCNLCH KVFRTLNSLN  60
   61 NHKSIYHRRQ KNHHSYFHHG AGVSQAGSPG SRLHQSLSSL SAAAAAANNS VNVGGGSVGG 120
  121 AGGNAVAAAA AAAAAAAELL LSPIVGAAAV AGGTASSTLQ LAAAHQQQQQ QSSPGIVKPC 180
  181 MDFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.045757
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle