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View Structure Prediction Details

Protein: br-PI, br-PH, br...
Organism: Drosophila melanogaster
Length: 880 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for br-PI, br-PH, br....

Description E-value Query
Range
Subject
Range
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
578.0 [0..111] [878..461]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTQHFCLR WNNYQSSITS AFENLRDDEA FVDVTLACEG RSIKAHRVVL SACSPYFREL  60
   61 LKSTPCKHPV ILLQDVNFMD LHALVEFIYH GEVNVHQKSL QSFLKTAEVL RVSGLTQQQA 120
  121 EDTHSHLAQI QNLANSGGRT PLNTHTQSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #2
Region A:
Residues: [150-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHPHHGSLHD DGGSSTLFSR QGAGSPPPTA VPSLPSHINN QLLKRMAMMH RSSAAAAAEE  60
   61 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHAFKRLRGS DNSLPLSGAV GSGSNNNSPD LPPLHARSAS PQQTPADFST IKHHNNNNTP  60
   61 PLKEEKRNGP TGNGNSGNGN GNGNGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [297-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGNGISISD KLGSLTPSPL ARAGADDVKS EPMDMVCSNN NANANDEHSN DSTGEHDANR  60
   61 SSSGDGGKGS LSSGNDEEIG DGLASHHAAP QFIMSPAENK MFHAAAFNFP NIDPSALLGL 120
  121 NTQLQQSGDL AVSPQGGSTG SLLSGVIVPG GSGGTPSNSS SNNNNNNSNN QQQKVEQQSS 180
  181 PHQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [480-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLQQQHHSTP HTNSPQLKQE QPKSGGGSCK SSDLHIAAGS ERSLSRSSQG MPDAGGHSAT  60
   61 PSPTAAYHKR ERERERERER ERERERERSL DHERDLERPG GTGSPPPPPP SHHSHFGQHP 120
  121 LSLLPSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [607-696]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQLHATHHEL SAAAAHHAHA HAHAAHAHAL ARAGSPMEHH HLLHHRRASL SPSGAVSSAS  60
   61 GAGGRGGGAG GPGGPGGSLL SSVRAQDVAQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [697-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANRLLLPLPL NACHRCDVCG KLLSTKLTLK RHKEQQHLQP LNNAVCNLCH KVFRTLNSLN  60
   61 NHKSIYHRRQ KNHHSYFHHG AGVSQAGSPG SRLHQSLSSL SAAAAAANNS VNVGGGSVGG 120
  121 AGGNAVAAAA AAAAAAAELL LSPIVGAAAV AGGTASSTLQ LAAAHQQQQQ QSSPGIVKPC 180
  181 MDFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.045757
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle