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View Structure Prediction Details

Protein: Ppox-PA
Organism: Drosophila melanogaster
Length: 475 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ppox-PA.

Description E-value Query
Range
Subject
Range
gi|108880710, gi... - gi|157138076|ref|XP_001657226.1| Protoporphyrinogen IX oxidase, putative [Aedes aegypti], gi|1088807...
233.0 [0..4] [471..3]

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Predicted Domain #1
Region A:
Residues: [1-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTAVLGGGL SGLSAGYYLL RRFGKPLTIY EASPRVGGWV RSENRKDRNF IFESGPRTIR  60
   61 PVGEPGANTL ELVEDLKLEV TPIRRSHVAA RNRMLYAKGQ LCMLPNSPKG LFGVLPPFTK 120
  121 PLYKAVLRDL FTASKKAKLE DESIYSFAER RFGKEIADYA ISPMICGICA GDAREISVRF 180
  181 LMEGLFEKEQ KYGGVLKGTL ISRFEKNKTK DTKDGLFAER QPKLYAQAVK EKWAMYGLKG 240
  241 GLENLPKTMR KYLGERDVNV QLSNECRNLT FSSSGVRMNI KDAEVPVEHV VSSLPAYKLA 300
  301 PLVKQQHPSL SAQLLSIPYV DVLVVNMQFP GKLLKQDGFG LLVPPVEKLP LLGVIFDSCC 360
  361 FDMGENTVLT VMMGGHWFDQ WFGDRPSPKQ ILDLATSHVQ KMLQIREEPK FSRVHTLHKC 420
  421 IPQYTVGHKR RVEAIRNYIK TYKLPLSVCG AAYDGVGIND VILSARRQVE AIPLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 2ivdA
Description: No description for 2ivdA was found.

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on NADH or NADPH 5.26950448055146 bayes_pls_golite062009
oxidoreductase activity 2.2944515778721 bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity 1.3578742399915 bayes_pls_golite062009
binding 1.26657667590853 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 1.20561532241252 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.07656675953489 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 0.945028138297487 bayes_pls_golite062009
transporter activity 0.890824576391732 bayes_pls_golite062009
transmembrane transporter activity 0.706117386114413 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.705416796630992 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 0.575252508985992 bayes_pls_golite062009
substrate-specific transporter activity 0.491481205015383 bayes_pls_golite062009
nucleic acid binding 0.386071802386842 bayes_pls_golite062009
transcription regulator activity 0.284200164472054 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.26114823844682 bayes_pls_golite062009
DNA binding 0.175069486065946 bayes_pls_golite062009
ferrous iron binding 0.166200528859874 bayes_pls_golite062009
protein binding 0.0281459437915129 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle