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View Structure Prediction Details

Protein: FBpp0297671, FBp...
Organism: Drosophila melanogaster
Length: 1383 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0297671, FBp....

Description E-value Query
Range
Subject
Range
gi|3859889, gi|7... - gi|7511827|pir||T13936 collar protein isoform C - fruit fly (Drosophila melanogaster), gi|3859889|gb...
1003.0 [0..88] [1346..1]

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Predicted Domain #1
Region A:
Residues: [1-146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISNKKSYAM KMLQLALALS LLHYNPDYLL HRWDSQLELG THGDGWELEM LRTVHRLDMD  60
   61 HNPYGNRKGL SPRIEDLLNF DDPSLGGMAN GIGGCKLPPR FNGSTFVMNL HNTTGNSSVQ 120
  121 TAALQDVQST SAAATGGTMV VGTGGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [147-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSGGQTSGS ALGEIHIDTA SLDPGNANHS PLHPTSELDT FLTPHALQDQ RSIWEQNLAD  60
   61 LYDYNDLSLQ TSPYANLPLK DGQPQPSNSS HLDLSLAALL HGFTGGSGAP LSTAALNDST 120
  121 PHPRNLGSVT NNSAGRSDDG EESLYLGRLF GEDEDEDYEG ELIGGVANAC EVEGLTTDEP 180
  181 FGSNCFANEV EIGDDEEESE IAEVLYKQDV DLGFSLDQEA IINASYASGN SAATNVKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [385-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPEDETKSSD PSISESSGFK DTDVNAENEA SAASVDDIEK LKALEELQQD KDKNNENQLE  60
   61 DITNEWNGIP FTIDNETGEY IRLPLDELLN DVLKLSEFPL QDDLSNDPVA STSQAAAAFN 120
  121 ENQAQRIVSE TGEDLLSGEG ISSKQNRNEA KNKDNDPEKA DGDSFSVSDF EELQNSVGSP 180
  181 LF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [567-732]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDEDAKKEL DEMLQSAVPS YHHPHPHHGH PHAHPHSHHH ASMHHAHAHH AAAAAAAHQR  60
   61 AVQQANYGGG VGVGVGVGVG VGSGTGSAFQ RQPAAGGFHH GHHQGRMPRL NRSVSMERLQ 120
  121 DFATYFSPIP SMVGGVSDMS PYPHHYPGYS YQASPSNGAP GTPGQH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [733-953]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQYGSGANAT LQPPPPPPPP HHAAMLHHPN AALGDICPTG QPHYGHNLGS AVTSSMHLTN  60
   61 SSHEADGAAA AAAAYKVEHD LMYYGNTSSD INQTDGFINS IFTDEDLHLM DMNESFCRMV 120
  121 DNSTSNNSSV LGLPSSGHVS NGSGSSAQLG AGNPHGNQAN GASGGVGSMS GSAVGAGATG 180
  181 MTADLLASGG AGAQGGADRL DASSDSAVSS MGSERVPSLS D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [954-1022]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEWGEGSDSA QDYHQGKYGG PYDFSYNNNS RLSTATRQPP VAQKKHQLYG KRDPHKQTPS  60
   61 ALPPTAPPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1023-1152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AATAVQSQSI KYEYDAGYAS SGMASGGISE PGAMGPALSK DYHHHQPYGM GASGSAFSGD  60
   61 YTVRPSPRTS QDLVQLNHTY SLPQGSGSLP RPQARDKKPL VATKTASKGA SAGNSSSVGG 120
  121 NSSNLEEEHL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1153-1187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRDEKRARSL NIPISVPDII NLPMDEFNER LSKYD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.85
Match: 1sknP
Description: Skn-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.16116926111366 bayes_pls_golite062009
transcription regulator activity 2.56809196773333 bayes_pls_golite062009
DNA binding 2.51449794308849 bayes_pls_golite062009
nucleic acid binding 2.33205906020933 bayes_pls_golite062009
transcription factor activity 2.10638151979258 bayes_pls_golite062009
protein binding 1.64791933694023 bayes_pls_golite062009
protein heterodimerization activity 0.735602594031742 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.483017958550706 bayes_pls_golite062009
protein dimerization activity 0.26737339325017 bayes_pls_golite062009
transcription activator activity 0.235928504008492 bayes_pls_golite062009

Predicted Domain #9
Region A:
Residues: [1188-1267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSENQLSLIR DIRRRGKNKV AAQNCRKRKL DQILTLEDEV NAVVKRKTQL NQDRDHLESE  60
   61 RKRISNKFAM LHRHVFQYLR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1hjbA
Description: C/ebp beta
Matching Structure (courtesy of the PDB):

Predicted Domain #10
Region A:
Residues: [1268-1383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEGNPCSPA DYSLQQAADG SVYLLPREKS EGNNTATAAS NAVSSASGGS LNGHVPTQAP  60
   61 MHSHQSHGMQ AQHVVGGMSQ QQQQQSRLPP HLQQQHHLQS QQQQPGGQQQ QQHRKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle