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View Structure Prediction Details

Protein: CG6194-PA
Organism: Drosophila melanogaster
Length: 668 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6194-PA.

Description E-value Query
Range
Subject
Range
gi|17862242 - gi|17862242|gb|AAL39598.1| LD17482p [Drosophila melanogaster]
910.0 [0..16] [668..1]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYDGLLSKL TDEKLMLFEA AGEGTIVEGS RICGQDADPL SLPLVEDGAI EEEQAAPIQT  60
   61 IHRTVFAVPR VPSPSPVSTS GANLNLKTEN AATATPQRKI STSSRFMNAF SQLYGGGNSG 120
  121 PSCGHV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [127-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQHNEEPGDL SANRTPTKGM ESKLVAMWHN VKYGWSGKMR QTSFSKEQPV WLLGRCYHRR  60
   61 FTPPVSM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [194-668]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSITELPSG ADTTPDNATS AFDSIQATST STSLYPALNP QQIDEIVVPQ ELGMDAVENQ  60
   61 VGEQPWEEGI EGFRRDFYSR IWMTYRREFP IMNGSNYTSD CGWGCMLRSG QMLFAQGLIC 120
  121 HFLGRSWRYD SESQLHSTYE DNMHKKIVKW FGDSSSKSSP FSIHALVRLG EHLGKKPGDW 180
  181 YGPASVSYLL KHALEHAAQE NADFDNISVY VAKDCTIYLQ DIEDQCSIPE PAPKPHVPWQ 240
  241 QAKRPQAETT KTEQQQHWKS LIVLIPLRLG SDKLNPVYAH CLKLLLSTEH CLGILGGKPK 300
  301 HSLYFVGFQE DRLIHLDPHY CQEMVDVNQE NFSLHSFHCK SPRKLKASKM DPSCCIGFYC 360
  361 ATKSDFDNFM ESVQLYLHPM RCASGATVDK AAGSHHTTPQ SSHQTEQTEM NYPLFSFSRG 420
  421 RCMDHERDEM SDSLYKPLIK QVASLAQELG AQLAPPQHGD EHDQDDSESE EFVLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 147.0
Match: 2d1iA
Description: Structure of human Atg4b
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
cysteine-type peptidase activity 3.05412701733177 bayes_pls_golite062009
hydrolase activity 2.66167923792227 bayes_pls_golite062009
cytoskeletal protein binding 2.13397229861051 bayes_pls_golite062009
small conjugating protein-specific protease activity 2.06332547782769 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
tubulin binding 1.85112496470487 bayes_pls_golite062009
microtubule binding 1.82320858139311 bayes_pls_golite062009
binding 1.77258741259391 bayes_pls_golite062009
ubiquitin-specific protease activity 1.43988355875744 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
nucleic acid binding 0.913227912866975 bayes_pls_golite062009
protein binding 0.896934807256194 bayes_pls_golite062009
transporter activity 0.69523261160023 bayes_pls_golite062009
DNA binding 0.683141655614916 bayes_pls_golite062009
transcription regulator activity 0.667279936700542 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.467924587720185 bayes_pls_golite062009
transmembrane transporter activity 0.439003000540428 bayes_pls_golite062009
structural molecule activity 0.297752217869698 bayes_pls_golite062009
calcium-dependent cysteine-type endopeptidase activity 0.196538841514154 bayes_pls_golite062009
substrate-specific transporter activity 0.125654358663332 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0241561776323942 bayes_pls_golite062009
transcription factor activity 0.0199148741009585 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle