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View Structure Prediction Details

Protein: CG31100-PA
Organism: Drosophila melanogaster
Length: 716 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31100-PA.

Description E-value Query
Range
Subject
Range
gi|49527412 - gi|49527412|emb|CAG61052.1| unnamed protein product [Candida glabrata]
gi|50291337, gi|... - gi|50291337|ref|XP_448101.1| unnamed protein product [Candida glabrata], gi|49527412|emb|CAG61052.1|...
307.0 [0..15] [534..84]

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Predicted Domain #1
Region A:
Residues: [1-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNGKAATAG ATAEKNGSLN DRPLFMQNGN GGRIATSDVE VSNFRRALPQ FLAVSIKNIL  60
   61 LFGYGMTLGF PTIVIPAIQG GEGRSETSGD ILLNKDEISW FSSINLICVP LGCLFSGLLT 120
  121 QPLGKRRAMQ FVNLPILAAW LMFHFATRTE HLYAALCLAG LGGGLMEAPV LTYVAEITEP 180
  181 KYRGILSALG TTCVITGVFI QFILGSLMDW RSVAAVSSAF PVITIIMLCF VPESPVWLIR 240
  241 EQRFREAVKS LQWLRGWVPE HMIEAEFNQL YDELITQKAI ELSADGIPPP GQRRTLGQRL 300
  301 RMWRKRSFLV PFLLVSFSFF TGHFSGKTPL QTYAVQIFHT LKAPMNKYHA TILLGVAEML 360
  361 ATILGVVLIH FTGKRPLVLV STVGTGLCFF GTATYAHFLS EVPGFTVNNV VVNASSIMPK 420
  421 EGILSQQNIS KIFETEQQAI RQETERFTTQ LPDIETTTLF DQEIYNRSRR DVVEMMTTDA 480
  481 PMDTTMWPEP SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.20943245291378 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.20943245291378 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
binding 0.805286077372817 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [493-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEPIASSSL APPSTSVKPP LVEELLLVVP KQEHNYLVWV PLILLLLSAF FSHLGIRMLP  60
   61 WILIGEVFPA EIRNSASGFA GGVGYIFGFL ANKLFLLMLS ALTLPGTFAF YASVAFFGTV 120
  121 VLYFTLPETE GRTLGEIEAH FSKKSDVNLL RKQPSNKLPI KDEAQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.5
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [658-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPGNTINMQG NFQVPITSTQ QTKIIHLQQS DFTPRSQNGR TAGVGLSNPA FEESNTTHL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.22
Match: 1rw6A
Description: human APP core domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle