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View Structure Prediction Details

Protein: osk-PA
Organism: Drosophila melanogaster
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for osk-PA.

Description E-value Query
Range
Subject
Range
gi|54639252, gi|... - gi|54639252|gb|EAL28654.1| GA10627-PA [Drosophila pseudoobscura], gi|125777137|ref|XP_001359508.1| G...
488.0 [0..27] [606..1]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVTSEFPS KPISYTSTNT SAKTYYLKSV KKRVTTCFQQ LRDKLQSSGS FRKSSSSCLN  60
   61 QIFVRSDFSA CGERFRKIFK SARKTELPEL WKVPLVAHEL TSRQSSQQLQ VVARLFSSTQ 120
  121 ISTKEITYNS NSNTSENNMT IIE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [144-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNYISVREEY PDIDSEVRAI LLSHAQNGIT ISSIKSEYRK LTGNPFPLHD NVTDFLLTIP  60
   61 NVTAECSESG KRIFNLKASL KNGHLLDMVL NQKERTSDYS SGAPSLENIP RAPPRYWKNP 120
  121 FKRRALSQLN TSPRTVPKIT DEKTKDIATR PVSLHQMANE AAESNWCYQD NWKHLNNFYQ 180
  181 QASVNA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [330-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKMPVPINIY SPDAPEEPIN LAPPGHQPSC RTQSQKTEPT ENRHLGIFVH PFNGMNIMKR  60
   61 RHEMTPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [397-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTILTSGTYN DSLLTINSDY DAYLLDFPLM GDDFMLYLAR MELKCRFRRH ERVLQSGLCV  60
   61 SGLTINGARN RLKRVQLPEG TQIIVNIGSV DIMRGKPLVQ IEHDFRLLIK EMHNMRLVPI 120
  121 LTNLAPLGNY CHDKVLCDKI YRFNKFIRSE CCHLKVIDIH SCLINERGVV RFDCFQASPR 180
  181 QVTGSKEPYL FWNKIGRQRV LQVIETSLEY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.045757
Match: 1jrlA
Description: Thioesterase I, TAP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.5922433129317 bayes_pls_golite062009
binding 1.48824074563071 bayes_pls_golite062009
catalytic activity 1.15974340242656 bayes_pls_golite062009
hydrolase activity 0.45071330223777 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0322595213897547 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle