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View Structure Prediction Details

Protein: FBpp0311305, FBp...
Organism: Drosophila melanogaster
Length: 763 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311305, FBp....

Description E-value Query
Range
Subject
Range
gi|76623405 - gi|76623405|ref|XP_887304.1| PREDICTED: similar to transcription elongation regulator 1 isoform 3 [B...
261.0 [0..314] [757..1]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDASLEESMD SDGASSPITK TEATESPPEA GLNGNGSGSG STSQETPNYG VAILKEKPSE  60
   61 AHRSKPFNAF SGRPIGEHTA QQQALQQQQL QQQQQPQQPQ QQAPSGANGV TGPPEIWVET 120
  121 KAEDGRSYYY HAVTRETTWS RPDGPAVKIM TQAEVEEMAK R

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.37
Match: 1o6wA
Description: Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.182048695645 bayes_pls_golite062009
binding 3.08386768818066 bayes_pls_golite062009
transcription activator activity 2.05338377709657 bayes_pls_golite062009
transcription factor binding 1.94857953695695 bayes_pls_golite062009
transcription cofactor activity 1.79381302696181 bayes_pls_golite062009
transcription coactivator activity 1.67777735708173 bayes_pls_golite062009
protein binding 1.17020309171645 bayes_pls_golite062009
catalytic activity 0.231344568578849 bayes_pls_golite062009
transcription repressor activity 0.135918306396444 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [162-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAQAAKTEAK AGETSVEIPP VSSHLTSQPP PHLMSQPPPN AAAPLLSQPP PNVRQQPPPM  60
   61 FQPPGMQAPP GFGQPPFCMP PPTYGFPGGP APAGAPWGVG IPPWQQQQHM QDKPAKSLII 120
  121 KPGVIDPAVI ARAAEWSEHR APDGRPYYF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [311-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HAGRGESVWE KPQALRDMEA ARMAAHSGVA PAVATAPSGL PPHLLPNPMM HMPPGSGPPG  60
   61 FDPHAAFAAA AAAMKANSEN TKAAQAAALE KEAKKAAEEK RKKEEEQKKA AASAKQTDKS 120
  121 RPVTSTPIAG TPWCVVWTGD SRVFFYNPST RTSVWDRPED LLNREDVDKA VNERPEQLKT 180
  181 PQEKSAEAEQ KSGEEANQEQ AK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.27
Match: 1o6wA
Description: Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.182048695645 bayes_pls_golite062009
binding 3.08386768818066 bayes_pls_golite062009
transcription activator activity 2.05338377709657 bayes_pls_golite062009
transcription factor binding 1.94857953695695 bayes_pls_golite062009
transcription cofactor activity 1.79381302696181 bayes_pls_golite062009
transcription coactivator activity 1.67777735708173 bayes_pls_golite062009
protein binding 1.17020309171645 bayes_pls_golite062009
catalytic activity 0.231344568578849 bayes_pls_golite062009
transcription repressor activity 0.135918306396444 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [513-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQVQAQQLDQ VQRVDADDDD DDEVIKIRTE SESSVEEVPT KRVRMISK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [561-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKRAEDAALE AEQRAAKERA LVPLEMRVTQ FKEMLREKDV SAFSTWEKEL HKIVFDPRYL  60
   61 LLTSKERKQV FEKY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.09691
Match: 2dodA
Description: No description for 2dodA was found.

Predicted Domain #6
Region A:
Residues: [635-763]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKDRAEEERK EKRNKMRQKR EDFRSLMEEA RLHGKSSFSE FSQRNAKDER YRAIEKVRER  60
   61 ESLFNEYIVE VRRREKEDKL LKKEQPLASR LQHKCTTQNT KIHKSNSIEN HLYNTLDGLF 120
  121 RPPSAIAVH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 2e71A
Description: No description for 2e71A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle