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View Structure Prediction Details

Protein: Syx7-PB, Syx7-PA
Organism: Drosophila melanogaster
Length: 282 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Syx7-PB, Syx7-PA.

Description E-value Query
Range
Subject
Range
gi|109099266 - gi|109099266|ref|XP_001111568.1| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]
189.0 [0..27] [280..131]
gi|50759625 - gi|50759625|ref|XP_417710.1| PREDICTED: similar to guanylate binding protein [Gallus gallus]
185.0 [0..1] [281..1048]
gi|73958357 - gi|73958357|ref|XP_547038.2| PREDICTED: similar to Syntaxin-1B2 (Syntaxin 1B) (P35B) [Canis familiar...
166.0 [0..15] [258..32]
gi|220777, gi|285304 - pir||A38141 neuronal cell membrane antigen HPC-1 - rat (fragment), gi|220777|dbj|BAA01231.1| HPC-1 ...
157.0 [0..20] [278..40]
STX2 - syntaxin 2
155.0 [0..20] [280..29]
gi|114647809 - gi|114647809|ref|XP_001138080.1| PREDICTED: syntaxin 2 [Pan troglodytes]
155.0 [0..20] [280..29]

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Predicted Domain #1
Region A:
Residues: [1-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLQHMENGL SGGGGGGLSE IDFQRLAQII ATSIQKVQQN VSTMQRMVNQ LNTPQDSPEL  60
   61 KKQLHQIMTY TNQLVTDTNN QINEVDKCKE RHLKIQRDRL VDEFTAALTA FQSVQRKTAD 120
  121 IEKTALRQAR GDSYNIARPP GSSRTGSSNS SASQQDNNSF FEDNFFNRKS NQQQMQTQME 180
  181 EQADLQALEE QEQVIRELEN NIVGVNEIYK KLGALVYEQG LTVDSIESQV EQTSIFVSQG 240
  241 TENLRKASSY RNKVRKKKLI LVGILSAVLL AIILILVFQF KN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 1dn1B
Description: Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
binding 2.33192450173199 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
substrate-specific transporter activity 1.2360389745429 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
protein transporter activity 0.81087535212264 bayes_pls_golite062009
SNARE binding 0.71459772253941 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.398018181744571 bayes_pls_golite062009
extracellular ligand-gated ion channel activity 0.27873535382283 bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity 0.27873535382283 bayes_pls_golite062009
ion transmembrane transporter activity 0.0981818568206971 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle