YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0304386, Syx...
Organism:	Drosophila melanogaster
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304386, Syx....

Description	E-value	Query Range	Subject Range
gi\|109099266 - gi\|109099266\|ref\|XP_001111568.1\| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]	165.0	[0..51]	[282..131]
gi\|50759625 - gi\|50759625\|ref\|XP_417710.1\| PREDICTED: similar to guanylate binding protein [Gallus gallus]	153.0	[0..44]	[283..1064]
gi\|73958357 - gi\|73958357\|ref\|XP_547038.2\| PREDICTED: similar to Syntaxin-1B2 (Syntaxin 1B) (P35B) [Canis familiar...	153.0	[0..14]	[258..11]
gi\|220777, gi\|285304 - pir\|\|A38141 neuronal cell membrane antigen HPC-1 - rat (fragment), gi\|220777\|dbj\|BAA01231.1\| HPC-1 ...	149.0	[0..7]	[278..1]
gi\|118404044, gi... - gi\|118404044\|ref\|NP_001072191.1\| syntaxin 1A (brain) [Xenopus (Silurana) tropicalis], gi\|110645670\|g...	146.0	[0..17]	[275..4]
gi\|531458, gi\|74... - gi\|7447071\|pir\|\|G01485 syntaxin - human, gi\|531458\|gb\|AAA20940.1\| syntaxin [Homo sapiens]	144.0	[0..44]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKALNNPGG NGGGGGPHRD YGAMADSTPE VSFAAAGGSS GFSPTEFMSL SEDIGHNITA  60
   61 IHSSTKQLEK QLKLIGTSKE QPNLREKVHT INTKCNARVQ TTSQDLQRLQ AVVRHGDRQQ 120
  121 KLQLEKLTRE FHGVVEKYSN LQRRISSAMR QTLQQAQQFA DQVVETNARA ELLQQQRLEQ 180
  181 AHLQQEHDML DDRRRQVEQI ESDIIDVNQI MTQLSGLVHD QGQQMDFIEN SIEQTAANVE 240
  241 DGTSELAKAA RSRQSYRRKI LILLVIAVII GLIVTGVIVA KLNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.30103
Match:	1dn1B
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNAP receptor activity	3.50393203740159	bayes_pls_golite062009
binding	2.90318399946307	bayes_pls_golite062009
SNARE binding	1.85060343142976	bayes_pls_golite062009
transporter activity	1.74189664015129	bayes_pls_golite062009
protein binding	1.51700626946713	bayes_pls_golite062009
substrate-specific transporter activity	1.49085442233849	bayes_pls_golite062009
transmembrane transporter activity	1.13101548288086	bayes_pls_golite062009
protein transporter activity	1.09007120264887	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.643064875848901	bayes_pls_golite062009
ion transmembrane transporter activity	0.370484918396857	bayes_pls_golite062009
extracellular ligand-gated ion channel activity	0.27873535382283	bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity	0.27873535382283	bayes_pls_golite062009
phospholipid binding	0.0172309833091902	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: