YRC Public Data Repository - Protein Structure Prediction

Protein:	CG5537-PA, FBpp0...
Organism:	Drosophila melanogaster
Length:	261 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5537-PA, FBpp0....

Description	E-value	Query Range	Subject Range
UPP_LACLM - Uracil phosphoribosyltransferase OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=upp PE=3 S... gi\|599847 - gi\|599847\|emb\|CAA51755.1\| uracil phosphoribosyltransferase [Lactococcus lactis] UPP_LACLC - Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase) - Lactococcus lactis...	247.0	[0..60]	[260..1]
UPP_LACLA - Uracil phosphoribosyltransferase OS=Lactococcus lactis subsp. lactis (strain IL1403) GN=upp PE=3 SV=... UPP_LACLA - Uracil phosphoribosyltransferase OS=Lactococcus lactis subsp. lactis GN=upp PE=3 SV=1	247.0	[0..60]	[260..1]
UPP_LACLS - Uracil phosphoribosyltransferase OS=Lactococcus lactis subsp. cremoris (strain SK11) GN=upp PE=3 SV=...	245.0	[0..60]	[260..1]
gi\|229331222, gi... - gi\|229497796\|ref\|ZP_04391495.1\| uracil phosphoribosyltransferase [Geobacillus sp. Y412MC52], gi\|2293... gi\|1765902, gi\|2... - gi\|21465611\|pdb\|1I5E\|B Chain B, Crystal Structure Of Bacillus Caldolyticus Uracil Phosphoribosyltran... UPP_GEOKA - Uracil phosphoribosyltransferase OS=Geobacillus kaustophilus GN=upp PE=3 SV=1 gi\|220709118, gi... - gi\|221087065\|ref\|ZP_03556605.1\| uracil phosphoribosyltransferase [Geobacillus sp. Y412MC61], gi\|2207... UPP_GEOKA - Uracil phosphoribosyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=upp PE=3 SV=1	242.0	[0..60]	[260..1]
UPP_STRSL - Uracil phosphoribosyltransferase OS=Streptococcus salivarius GN=upp PE=3 SV=1 gi\|228476631, gi... - gi\|228476631\|ref\|ZP_04061313.1\| uracil phosphoribosyltransferase [Streptococcus salivarius SK126], g...	242.0	[0..60]	[260..1]
UPP_PEDPA - Uracil phosphoribosyltransferase OS=Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) GN=upp PE=3...	241.0	[0..60]	[260..1]
gi\|55736433, gi\|... - gb\|AAV61958.1\| uracil phosphoribosyltransferase [Streptococcus thermophilus CNRZ1066], gb\|AAV60075.... UPP_STRT2 - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) GN=... UPP_STRTD - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) GN=upp ... UPP_STRT1 - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain CNRZ 1066) GN=upp PE=3 SV=1	241.0	[0..60]	[260..1]
gi\|89089364, gi\|... - gi\|89095618\|ref\|ZP_01168512.1\| uracil phosphoribosyltransferase [Bacillus sp. NRRL B-14911], gi\|8908...	240.0	[0..60]	[260..1]
UPP_STRMU - Uracil phosphoribosyltransferase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) GN=... gi\|254996869 - gi\|254996869\|dbj\|BAH87470.1\| uracil phosphoribosyltransferase [Streptococcus mutans NN2025] UPP_STRMU - Uracil phosphoribosyltransferase OS=Streptococcus mutans GN=upp PE=3 SV=1	239.0	[0..60]	[260..1]
gi\|223933329, gi... - gi\|81097024\|ref\|ZP_00875340.1\| Uracil phosphoribosyl transferase [Streptococcus suis 89/1591], gi\|80...	238.0	[0..60]	[260..1]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTGSPSSSG SQSEEGSSSS DHQQPQQEAQ EQEQQLHTPT HAHAAVPAAT SEEILAEYGS  60
   61 NLKLLECNSQ VAELLTILRD KNTTRSDFKF YADRLIRLVI EESLNQLPYT HCDVETPTGA 120
  121 IYEGLKYRSG NCGVSIIRSG EAMEQGLRDC CRSIRIGKIL VESDANTHEA RVVYARFPDD 180
  181 IGSRQVLLMY PIMSTGNTVL QAVNVLREHG VPESCIILSN LFCTPIAART VVNAFPKLKI 240
  241 LTSELHPVAP NHFGQKYFGT D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.09691
Match:	1bd3D
Description:	Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil phosphoribosyltransferase activity	3.97944228585882	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	3.07502596276449	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.67945744445872	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	0.947697983706416	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.730385736169604	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.360901350940423	bayes_pls_golite062009
purine binding	0.358545436706029	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: