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View Structure Prediction Details

Protein: Vti1-PA
Organism: Drosophila melanogaster
Length: 230 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Vti1-PA.

Description E-value Query
Range
Subject
Range
gi|73999473 - gi|73999473|ref|XP_544116.2| PREDICTED: similar to vesicle transport through interaction with t-SNAR...
168.0 [0..2] [220..177]
VTI13_ARATH - Vesicle transport v-SNARE 13 OS=Arabidopsis thaliana GN=VTI13 PE=2 SV=1
141.0 [0..4] [220..5]
gi|92883016 - gi|92883016|gb|ABE86759.1| Vesicle transport v-SNARE [Medicago truncatula]
139.0 [0..2] [220..3]
gi|114653589 - gi|114653589|ref|XP_510021.2| PREDICTED: similar to Retinol dehydrogenase 11 (all-trans/9-cis/11-cis...
139.0 [0..2] [178..415]
gi|46138669, gi|... - gi|46138669|ref|XP_391025.1| hypothetical protein FG10849.1 [Gibberella zeae PH-1], gi|42551459|gb|E...
137.0 [0..2] [195..12]
gi|50760647 - gi|50760647|ref|XP_418096.1| PREDICTED: similar to Wnt-9b protein precursor (Wnt-15) (Wnt-14b) [Gall...
137.0 [0..3] [218..490]
gi|39973459, gi|... - gi|39973459|ref|XP_368120.1| hypothetical protein MG01124.4 [Magnaporthe grisea 70-15], gb|EAA49466....
134.0 [0..2] [221..82]
gi|56754168 - gi|56754168|gb|AAW25272.1| unknown [Schistosoma japonicum]
134.0 [0..1] [230..1]
gi|54641548, gi|... - gi|54641548|gb|EAL30298.1| GA17139 [Drosophila pseudoobscura pseudoobscura], gi|125977530|ref|XP_001...
gi|54641548|gb|E... - GA17139-PA [Drosophila pseudoobscura], GA17139 [Drosophila pseudoobscura pseudoobscura]
133.0 [0..1] [229..1]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLEQYEQQ YATLIAEITA HIGRLQQQNN NSERHDLCSK IDSSLPEAQE LLEQMGLEVR  60
   61 ELNPGLRSSF NGKLQVAQAE LKRLQAEYRL TKDKQRSQAN TFTTLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 1vcsA
Description: Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatidic acid binding 6.29287857316152 bayes_pls_golite062009
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
calcium channel inhibitor activity 2.99240433552966 bayes_pls_golite062009
arachidonic acid binding 2.43181217934756 bayes_pls_golite062009
protein transporter activity 2.305772311362 bayes_pls_golite062009
binding 2.18404492932496 bayes_pls_golite062009
SNARE binding 1.85060343142976 bayes_pls_golite062009
protein binding 1.82422117934251 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
substrate-specific transporter activity 1.49085442233849 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.643064875848901 bayes_pls_golite062009
ion transmembrane transporter activity 0.370484918396857 bayes_pls_golite062009
channel activity 0.0647076360772156 bayes_pls_golite062009
passive transmembrane transporter activity 0.0647076360772156 bayes_pls_golite062009
substrate-specific channel activity 0.0435980899803177 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009
cytoskeletal protein binding 0.00476738027966683 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [107-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGDSYEDVSI STDQRQRLLD NSERIERTGN RLTEGYRVAL ETEQLGAQVL NDLHHQRETL  60
   61 QGARARLRET NAELGRASRT LNTMMLRALR EKVVLYGVGV CFVVAVGVSL YLTFAPSSSS 120
  121 TASS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 2npsC
Description: No description for 2npsC was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle