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View Structure Prediction Details

Protein: Nxt1-PA
Organism: Drosophila melanogaster
Length: 133 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Nxt1-PA.

Description E-value Query
Range
Subject
Range
gi|109131896 - gi|109131896|ref|XP_001098951.1| PREDICTED: nuclear transport factor 2-like export factor 2 isoform ...
167.0 [0..1] [132..58]
gi|76673500 - gi|76673500|ref|XP_590663.2| PREDICTED: similar to nuclear transport factor 2-like export factor 2 [...
167.0 [0..1] [132..149]
gi|94403170, gi|... - gi|94404128|ref|XP_988895.1| PREDICTED: similar to Nuclear transport factor 2 (NTF-2) [Mus musculus]...
166.0 [0..9] [130..4]
gi|9663147 - gi|9663147|emb|CAC01129.1| p15-2b protein [Homo sapiens]
164.0 [0..4] [132..52]
gi|50746525 - gi|50746525|ref|XP_420536.1| PREDICTED: similar to KIAA0660 protein [Gallus gallus]
162.0 [0..2] [132..84]
gi|40807189 - gi|40807189|gb|AAH65323.1| GTPase activating protein (SH3 domain) binding protein 1 [Danio rerio]
161.0 [0..5] [132..1]
gi|2914437, gi|2... - gi|2914437|pdb|1ASK|B Chain B, Nuclear Transport Factor 2 (Ntf2) H66a Mutant, gi|2914436|pdb|1ASK|A ...
160.0 [0..9] [130..4]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSDLKAKVE SCARTADTFT RLYYASVDNR RQQIGRLYLD NATLSWNGNG AIGRQMIESY  60
   61 FQELPSSNHQ LNTLDAQPIV DQAVSNQLAY LIMASGSVKF ADQQLRKFQQ TFIVTAENDK 120
  121 WKVVSDCYRM QEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.154902
Match: 1jkgA
Description: NTF2-related export protein 1 (p15)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleocytoplasmic transporter activity 4.11811310168752 bayes_pls_golite062009
protein transporter activity 3.2858716221712 bayes_pls_golite062009
protein transmembrane transporter activity 2.22367856601071 bayes_pls_golite062009
binding 2.08734227778958 bayes_pls_golite062009
RNA binding 1.98983420561953 bayes_pls_golite062009
transporter activity 1.80701285041353 bayes_pls_golite062009
mRNA binding 1.39091688795726 bayes_pls_golite062009
protein binding 1.36536670483288 bayes_pls_golite062009
substrate-specific transporter activity 1.33804818542017 bayes_pls_golite062009
structural constituent of nuclear pore 1.30758304562723 bayes_pls_golite062009
transmembrane transporter activity 1.22102896992563 bayes_pls_golite062009
Ran GTPase binding 1.18290069522408 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.890150150408175 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.87831089735211 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.87831089735211 bayes_pls_golite062009
primary active transmembrane transporter activity 0.446562877324676 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.439519001457896 bayes_pls_golite062009
active transmembrane transporter activity 0.430285640125175 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle