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View Structure Prediction Details

Protein: Klp59C-PA
Organism: Drosophila melanogaster
Length: 626 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Klp59C-PA.

Description E-value Query
Range
Subject
Range
gi|73949595 - gi|73949595|ref|XP_860516.1| PREDICTED: similar to Kinesin-like protein KIF2 (Kinesin-2) (HK2) isofo...
504.0 [0..3] [623..8]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKLSIEQKI FIRRSDGRVH LAEIIKLEGG DSKLITVEWP EGHTVRGKEL PLELVVLMNP  60
   61 HIFDSPRCSG GNAASANQTA SISPRSMKQR IATGSL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1wgsA
Description: Solution Structure of the Tudor Domain from Mouse Hypothetical Protein Homologous to Histone Acetyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chromatin binding 3.39903944543479 bayes_pls_golite062009
binding 2.96155744225842 bayes_pls_golite062009
protein binding 2.55372006358699 bayes_pls_golite062009
transcription regulator activity 1.73885652606576 bayes_pls_golite062009
histone binding 1.27264385817111 bayes_pls_golite062009
transcription repressor activity 1.11983876800692 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.621667574938228 bayes_pls_golite062009
nucleic acid binding 0.45690927871554 bayes_pls_golite062009
DNA binding 0.411003296485644 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.206602190936326 bayes_pls_golite062009
pyrophosphatase activity 0.163969786045852 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.153584983966247 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.151023160570585 bayes_pls_golite062009
transcription activator activity 0.102820714122071 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [97-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVLATAPPR QQTAPPVRED EVVHQAERMR KERERRREAQ ARTRLDREQG KNEDPGNPNW  60
   61 EVARMIRLQR EQMESQRVRS GTTNERINCH QIMVCVRKRP LRRKELADRE QDVVSIPSKH 120
  121 TLVVHEPRKH VNLVKFLENH SFRFDYVFDE ECSNATVYEF TARPLIKHIF DGGMATCFAY 180
  181 GQTGSGKTYT MGGQFPGRHQ SSMDGIYAMA AKDVFSTLKT VPYNKLNLKV YCSFFEIYGT 240
  241 RVFDLLMPGK PQLRVLEDRN QQVQVVGLTQ NPVQNTAEVL DLLELGNSVR TSGHTSANSK 300
  301 SSRSHAVFQI VLRSAAGEKL HGKFSLIDLA GNERGADNSS ADRQTRLEGS EINKSLLVLK 360
  361 ECIRALGRQS SHLPFRGSKL TQVLRDSFIG GKKVKTCMIA MISPCLHSVE HTLNTLRYAD 420
  421 RVKELSVESI PSKRM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.0
Match: 2gryA
Description: No description for 2gryA was found.

Predicted Domain #3
Region A:
Residues: [532-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDANLGSTSM SDIVCQSSTQ RLFPCASSTS MPGGGNQAQQ HTNTANDLNR SQKPTSKPTY  60
   61 PTSGQQLVQR KGSSQREASM MLTKSLAQFR GRNFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 2dfsA
Description: No description for 2dfsA was found.

YRC Informatics Platform - Version 3.0
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