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View Structure Prediction Details

Protein: MED23-PA
Organism: Drosophila melanogaster
Length: 1439 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED23-PA.

Description E-value Query
Range
Subject
Range
gi|114609395 - gi|114609395|ref|XP_527503.2| PREDICTED: cofactor required for Sp1 transcriptional activation, subun...
2158.0 [0..1] [1357..137]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METQVIDTVN EFLKVDSLDE AFVSVIVFKP NTEQERATRF ANDLVTAFGN VAQENREQVL  60
   61 RLYLLRAAGA SGYHIKVLMA ALVKLVDAHV ITARMLCDKV LMCEKLDFEH RTFWIESFRL 120
  121 IKRVIV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [127-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVDYKGVREI MKVCRDKAQW FPLNVNVTYM PQLLAVEDIL RFIFDRNNCL LPAYFIANEI  60
   61 MRPFPYHWKL NRLMTDFVEE FRTTAQMVSI IGHASMLPIV EHFG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [231-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YADHMMNSWR LDHNTLKFNF KGSLPYEPEL LEEQKPLLRY VLEQPYSREM VSQMLNLQK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [290-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQKQRYNALE EQLVNLIVQA MEMTEANDAT AGSGFNSSDE QITPYEWMWL HLSSQLIYFV  60
   61 LFQFVSFMHI VLALHEKLSK LELRKGRDQL MWILLQFISG SIQKNPITNF LPVFRLFDLL 120
  121 YPELEPLKLP DINKSSMVRH MAPICVWIHL MKKARVENMN ITR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [453-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPIALKNHY DFLQHLVTAN TMMNMTLGND FRIILICNAY STNQEYFGRP MGLLLDALNG  60
   61 TSKSPNGGQI PAVTFSVTVL DSLTVHSKMS L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [544-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHSFVTQMLK QAQSKGQVPA AALLETYARL LVYTEIESLG IKGFLSQLMP TVFKNHAWAM  60
   61 LHTLMEMFSY RLHHVPTHYR VQLLSLLHSL SSVPQTNKMQ LNLCFESTAL RLITSIGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [662-783]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEFQPQFSRY FNDKSPGAVA SNESEELNRV LILTLARSMH VHGGGDEMQG WCKDFLSNII  60
   61 QHTPHSWPMH SLACFPPALN EYFTQNNQPP ENKQQLKKAV EEEYRTWTSM TNENDIIAHF 120
  121 LR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [784-929]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTTNPLFLCL LFKIIWETEN ISPVAYKILE GISARALSTH LRKFCDYLVA EVASSSDGRD  60
   61 FIHKCVDTIN NMIWKFNVVT IDRVVLCLAL RTHEGNEAQV CFLIIQLLLL KASELRNRVQ 120
  121 EFCKDNNPDH WKQSNWQDKH LSFHQK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [930-1147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPEKFALDES ASQIPLPVYF SNVCLRFLPV LDVVVHRFIE LTITNVHQIL GFILDHLSIL  60
   61 YKFHDRPITY LYNTLHYYER ILRDRPALKK KLVGAITSAF SEIRPPNWSV SEPYKVYLQS 120
  121 QDSLWTPELS YYMSLIRRLA DTISGKNVFY STDWRFNEFP NAPTHALYVT CVELLGLPVA 180
  181 PPLVASNLID VIVSGYAVIP QKDIHSYINA VGIVLAAL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1148-1274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEPYWSGIYD RLQDMLNTPN MLNWTYRFNA FELFNFKTVR EAMLEKTYAV VLAVAHSVFH  60
   61 HMGAFKLAAM TRYLKEKLKP CVRTEQQLLY LCHVFGPFLQ RIELEKPNAV AGIAVLLYEI 120
  121 LEIVDKH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1275-1439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGPKPLQYMD QICDFLYHIK YIHVGNIIKN ESEAIIKRLR PLLQMRLRFI THLNLEDIHT  60
   61 EKINDNTSNN AITSQTQSPM QTQHQQQPQQ PHQQQQQQQQ QQQQQQQQQQ QQQQMQQQQI 120
  121 NAVQTTSVPL GSGGNLQQQQ QINQQQQMYM QHMQQHQHMQ NMRHN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle