YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MED23-PA

General Information:
Name(s) found: MED23-PA / FBpp0071814 [FlyBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • The gene Mediator complex subunit 23 is referred to in FlyBase by the symbol Dmel\MED23 (CG3695, FBgn0034795). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18776507..18783261. It has the cytological map location 59B4. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription mediator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    mediator complex [ISS]
    Biological Process: transcription from RNA polymerase II promoter [ISS]
    transcription initiation from RNA polymerase II promoter [ISS]
    Molecular Function: RNA polymerase II transcription mediator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METQVIDTVN EFLKVDSLDE AFVSVIVFKP NTEQERATRF ANDLVTAFGN VAQENREQVL  60
   61 RLYLLRAAGA SGYHIKVLMA ALVKLVDAHV ITARMLCDKV LMCEKLDFEH RTFWIESFRL 120
  121 IKRVIVQVDY KGVREIMKVC RDKAQWFPLN VNVTYMPQLL AVEDILRFIF DRNNCLLPAY 180
  181 FIANEIMRPF PYHWKLNRLM TDFVEEFRTT AQMVSIIGHA SMLPIVEHFG YADHMMNSWR 240
  241 LDHNTLKFNF KGSLPYEPEL LEEQKPLLRY VLEQPYSREM VSQMLNLQKH QKQRYNALEE 300
  301 QLVNLIVQAM EMTEANDATA GSGFNSSDEQ ITPYEWMWLH LSSQLIYFVL FQFVSFMHIV 360
  361 LALHEKLSKL ELRKGRDQLM WILLQFISGS IQKNPITNFL PVFRLFDLLY PELEPLKLPD 420
  421 INKSSMVRHM APICVWIHLM KKARVENMNI TRPLPIALKN HYDFLQHLVT ANTMMNMTLG 480
  481 NDFRIILICN AYSTNQEYFG RPMGLLLDAL NGTSKSPNGG QIPAVTFSVT VLDSLTVHSK 540
  541 MSLIHSFVTQ MLKQAQSKGQ VPAAALLETY ARLLVYTEIE SLGIKGFLSQ LMPTVFKNHA 600
  601 WAMLHTLMEM FSYRLHHVPT HYRVQLLSLL HSLSSVPQTN KMQLNLCFES TALRLITSIG 660
  661 SAEFQPQFSR YFNDKSPGAV ASNESEELNR VLILTLARSM HVHGGGDEMQ GWCKDFLSNI 720
  721 IQHTPHSWPM HSLACFPPAL NEYFTQNNQP PENKQQLKKA VEEEYRTWTS MTNENDIIAH 780
  781 FLRPTTNPLF LCLLFKIIWE TENISPVAYK ILEGISARAL STHLRKFCDY LVAEVASSSD 840
  841 GRDFIHKCVD TINNMIWKFN VVTIDRVVLC LALRTHEGNE AQVCFLIIQL LLLKASELRN 900
  901 RVQEFCKDNN PDHWKQSNWQ DKHLSFHQKY PEKFALDESA SQIPLPVYFS NVCLRFLPVL 960
  961 DVVVHRFIEL TITNVHQILG FILDHLSILY KFHDRPITYL YNTLHYYERI LRDRPALKKK1020
 1021 LVGAITSAFS EIRPPNWSVS EPYKVYLQSQ DSLWTPELSY YMSLIRRLAD TISGKNVFYS1080
 1081 TDWRFNEFPN APTHALYVTC VELLGLPVAP PLVASNLIDV IVSGYAVIPQ KDIHSYINAV1140
 1141 GIVLAALPEP YWSGIYDRLQ DMLNTPNMLN WTYRFNAFEL FNFKTVREAM LEKTYAVVLA1200
 1201 VAHSVFHHMG AFKLAAMTRY LKEKLKPCVR TEQQLLYLCH VFGPFLQRIE LEKPNAVAGI1260
 1261 AVLLYEILEI VDKHHGPKPL QYMDQICDFL YHIKYIHVGN IIKNESEAII KRLRPLLQMR1320
 1321 LRFITHLNLE DIHTEKINDN TSNNAITSQT QSPMQTQHQQ QPQQPHQQQQ QQQQQQQQQQ1380
 1381 QQQQQQQQMQ QQQINAVQTT SVPLGSGGNL QQQQQINQQQ QMYMQHMQQH QHMQNMRHN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] MSA 1.017951 View MSA. No confident structure predictions are available.
    2 View Details [127..230] deduced N/A No confident structure predictions are available.
    3 View Details [231..289] MSA 1.01798 View MSA. No confident structure predictions are available.
    4 View Details [290..452] deduced N/A No confident structure predictions are available.
    5 View Details [453..543] MSA 1.020986 View MSA. No confident structure predictions are available.
    6 View Details [544..661] deduced N/A No confident structure predictions are available.
    7 View Details [662..783] deduced N/A No confident structure predictions are available.
    8 View Details [784..929] MSA 1.023953 View MSA. No confident structure predictions are available.
    9 View Details [930..1147] deduced N/A No confident structure predictions are available.
    10 View Details [1148..1274] deduced N/A No confident structure predictions are available.
    11 View Details [1275..1439] MSA 1.019968 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle