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View Structure Prediction Details

Protein: CG3074-PB, CG3074-PA
Organism: Drosophila melanogaster
Length: 431 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG3074-PB, CG3074-PA.

Description E-value Query
Range
Subject
Range
gi|16768502 - gi|16768502|gb|AAL28470.1| GM06507p [Drosophila melanogaster]
359.0 [0..1] [431..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKCVHLVG LLVLLMGGAN ALFDHTLKRD FPGPYCAREN TCCKDRHDGC SVPISNTLCY  60
   61 CDEFCDRDDS SDCCPDYRSF CIGEVDPI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.31
Match: 2ys0A
Description: No description for 2ys0A was found.

Predicted Domain #2
Region A:
Residues: [89-431]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISCEHNGVYF SKYNTTWDNC NECRCLEGGS VQCDEDLCLT DDAIVHSVNS IHRLGWSARK  60
   61 YDQWWGRKYS EGLKLRLGTK EPTYRVKAMT RLKNPTDGLP SSFNALDKWS SYISEVPDQG 120
  121 WCGASWVLST TSVASDRFAI QSKGKENVQL SAQNILSCTR RQQGCEGGHL DAAWRYLHKK 180
  181 GVVDENCYPY TQHRDTCKIR HNSRSLRANG CQKPVNVDRD SLYTVGPAYS LNREADIMAE 240
  241 IFHSGPVQAT MRVNRDFFAY SGGVYRETAA NRKAPTGFHS VKLVGWGEEH NGEKYWIAAN 300
  301 SWGSWWGEHG YFRILRGSNE CGIEEYVLAS WPYVYSYYNV KSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.154902
Match: 1jqpA
Description: Dipeptidyl peptidase I (cathepsin C), exclusion domain; Cathepsin C (dipeptidyl peptidase I), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.90619850296986 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.64381885397949 bayes_pls_golite062009
endopeptidase activity 3.75054525912786 bayes_pls_golite062009
hydrolase activity 3.74079711298952 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
transporter activity 1.21845572420504 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
binding 1.05436445615005 bayes_pls_golite062009
transmembrane transporter activity 1.00091316610003 bayes_pls_golite062009
protein binding 0.896934807256194 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.649171767629235 bayes_pls_golite062009
thiolester hydrolase activity 0.59115205419466 bayes_pls_golite062009
substrate-specific transporter activity 0.484449686814032 bayes_pls_golite062009
kininogen binding 0.41283715939055 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.246369226539662 bayes_pls_golite062009
active transmembrane transporter activity 0.193338880082314 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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