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View Structure Prediction Details

Protein: GlcT-1-PA
Organism: Drosophila melanogaster
Length: 440 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GlcT-1-PA.

Description E-value Query
Range
Subject
Range
gi|54636877, gi|... - gi|54636877|gb|EAL26280.1| GA19592 [Drosophila pseudoobscura pseudoobscura], gi|125810981|ref|XP_001...
gi|54636877|gb|E... - GA19592-PA [Drosophila pseudoobscura], GA19592 [Drosophila pseudoobscura pseudoobscura]
230.0 [0..1] [440..1]

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Predicted Domain #1
Region A:
Residues: [1-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLPLPLYG FAAFFMVFWL GTWMVHVIAI CYGRYKLHKK SCKLPTEAQP LPGVSILKPL  60
   61 MGVDPNLQHN LETFFTMDYP LYELLFCVED KEDPAIQLVE RLLAKYPLVD AALFVGGSDV 120
  121 GVNPKINNIH PGYMAAKYDF VMISDSGIKM KDDTLLDMVQ NMSEKHALVH QMPFTCDRDG 180
  181 FAATFEKVFF GTVQSRIYLS ADVLGINCHT GMSCLLRKAV IDQLGGLRAF GCYLAEDFFI 240
  241 ARSVTRLGWK MRISNQPALQ NSGLCDIGSF QARLIRWAKL RVAMVPTTIL LE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1xhbA
Description: The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 3.91817804237674 bayes_pls_golite062009
galactosyltransferase activity 3.12982459519199 bayes_pls_golite062009
UDP-galactosyltransferase activity 2.85902170551357 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.59060425244283 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.3653525792322 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 2.34299829327848 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 2.33328124075323 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
transferase activity 1.47184463413038 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 1.35544202600014 bayes_pls_golite062009
nucleotidyltransferase activity 1.31793036737589 bayes_pls_golite062009
cytidylyltransferase activity 0.983416157001861 bayes_pls_golite062009
alpha-1,3-galactosyltransferase activity 0.93930146000871 bayes_pls_golite062009
mannosyltransferase activity 0.84124932672384 bayes_pls_golite062009
binding 0.667238976803188 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.361674579616957 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [293-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSECMILGA IAAWSASVLF SWDPLVFYLV HVLCWFLSDW LLLSIVQHGS MPFHKFEFVV  60
   61 GWLFRELTGP YLFLHALWNP AIRWRARTYK LHWGGVAYEL NSLASDAAND PLAPQPQPAP 120
  121 TLEPAVVNAG TTGDTLICTG AKQRLLVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle