| Protein: | Rx-PA |
| Organism: | Drosophila melanogaster |
| Length: | 873 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rx-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
319.0 | [0..1] | [873..32] |
|
Region A: Residues: [1-190] |
1 11 21 31 41 51
| | | | | |
1 MSGSGGVANS SSTAAANNTA ATFQHIFEQL VQQGGGNHKL PPKQLEQLRH LLGNVRDAKN 60
61 LQMIVEKFKN LEQFHEHYAA HLANNNTVIS TEDSNDLVKD NARKYGSGGQ TLTPRHTIDA 120
121 ILGLKNRNGA ANGSGRNPET VSDGSVDPSL GDDDATDLRC GMTLTQLRSM DNHMASMLQQ 180
181 HAKNGGALPY
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [191-362] |
1 11 21 31 41 51
| | | | | |
1 GPPTPPGGQQ PQVPNATPLH HGQQMGGQAG HATHAGHGHP THHGHAPFGY HNAFGFGQGG 60
61 HGYGHPEEAA GNYLNSMHQM VEANQLQTGA NGANPPPAPL PPSSFGSHQQ HLAALAAQAQ 120
121 EQQNQHSKYA KSSPTGAGPP PPPGAYFMES QTAPVAPSQI NYDERSMSSA SD
|
| Detection Method: | |
| Confidence: | 3.154902 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [363-497] |
1 11 21 31 41 51
| | | | | |
1 LEEDDDDAAK LQLDVTSPPT PSPRGQLAAK RKSAGVFCDD NEPKLANGQL PGGNYGIRPR 60
61 SMEEVHHQQQ SHHHQQQQQQ QQQQQQLQQQ QGFQHDFRNS GNGNPNGNSN SGDHGERLNA 120
121 DSDSLVNGSC ASSED
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [498-648] |
1 11 21 31 41 51
| | | | | |
1 LNQTNSSEQG EKITSGSDDE GQDDNCAKKK HRRNRTTFTT YQLHELERAF EKSHYPDVYS 60
61 REELAMKVNL PEVRVQVWFQ NRRAKWRRQE KSESLRLGLT HFTQLPHRLG CGASGLPVDP 120
121 WLSPPLLSAL PGFLSHPQTV YPSYLTPPLS L
|
| Detection Method: | |
| Confidence: | 10.154902 |
| Match: | 2cueA |
| Description: | Solution structure of the homeobox domain of the human paired box protein Pax-6 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [649-729] |
1 11 21 31 41 51
| | | | | |
1 APGNLTMSSL AAMGHHHAHN GPPPPHVGHG GHGQPQPPPP PPPHGVPHPH GSHHVVPLSH 60
61 LSPHLSRMSP HATSLGSPHH G
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [730-873] |
1 11 21 31 41 51
| | | | | |
1 VTPLGTPLHS SLPPSSTATT VAVSSSQSSS SSASLECSGP DVCMSPQNLS IGNADSNGDG 60
61 RDLSSDLDAG STSSNPGSSL DKCAASANIE LLDVGRDSPP PPPTPTGKGS STPPTDMRSN 120
121 SIATLRIKAK EHLDNLNKGM VSIV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
