YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Rx-PA
Organism: Drosophila melanogaster
Length: 873 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rx-PA.

Description E-value Query
Range
Subject
Range
gi|2950355 - gi|2950355|emb|CAA11241.1| homebox protein DRx [Drosophila melanogaster]
319.0 [0..1] [873..32]

Back

Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSGGVANS SSTAAANNTA ATFQHIFEQL VQQGGGNHKL PPKQLEQLRH LLGNVRDAKN  60
   61 LQMIVEKFKN LEQFHEHYAA HLANNNTVIS TEDSNDLVKD NARKYGSGGQ TLTPRHTIDA 120
  121 ILGLKNRNGA ANGSGRNPET VSDGSVDPSL GDDDATDLRC GMTLTQLRSM DNHMASMLQQ 180
  181 HAKNGGALPY 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [191-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPPTPPGGQQ PQVPNATPLH HGQQMGGQAG HATHAGHGHP THHGHAPFGY HNAFGFGQGG  60
   61 HGYGHPEEAA GNYLNSMHQM VEANQLQTGA NGANPPPAPL PPSSFGSHQQ HLAALAAQAQ 120
  121 EQQNQHSKYA KSSPTGAGPP PPPGAYFMES QTAPVAPSQI NYDERSMSSA SD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [363-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEEDDDDAAK LQLDVTSPPT PSPRGQLAAK RKSAGVFCDD NEPKLANGQL PGGNYGIRPR  60
   61 SMEEVHHQQQ SHHHQQQQQQ QQQQQQLQQQ QGFQHDFRNS GNGNPNGNSN SGDHGERLNA 120
  121 DSDSLVNGSC ASSED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [498-648]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNQTNSSEQG EKITSGSDDE GQDDNCAKKK HRRNRTTFTT YQLHELERAF EKSHYPDVYS  60
   61 REELAMKVNL PEVRVQVWFQ NRRAKWRRQE KSESLRLGLT HFTQLPHRLG CGASGLPVDP 120
  121 WLSPPLLSAL PGFLSHPQTV YPSYLTPPLS L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.154902
Match: 2cueA
Description: Solution structure of the homeobox domain of the human paired box protein Pax-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [649-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APGNLTMSSL AAMGHHHAHN GPPPPHVGHG GHGQPQPPPP PPPHGVPHPH GSHHVVPLSH  60
   61 LSPHLSRMSP HATSLGSPHH G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [730-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTPLGTPLHS SLPPSSTATT VAVSSSQSSS SSASLECSGP DVCMSPQNLS IGNADSNGDG  60
   61 RDLSSDLDAG STSSNPGSSL DKCAASANIE LLDVGRDSPP PPPTPTGKGS STPPTDMRSN 120
  121 SIATLRIKAK EHLDNLNKGM VSIV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle